I. Summary
SecReT6 ID673 insolico
StrainEnterobacter cloacae subsp. dissolvens SDM
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1A3UG_133152866102..2866479 [-], 378392979505hypothetical protein 
2A3UG_133202866618..2867694 [-], 1077392979506hypothetical protein 
3A3UG_133252867698..2868261 [-], 564392979507hypothetical protein 
4A3UG_133302868254..2868673 [-], 420392979508hypothetical protein 
5A3UG_133352868747..2870669 [-], 1923392979509hypothetical protein  TssI
6A3UG_133402870735..2871169 [-], 435392979510hypothetical protein 
7A3UG_133452871259..2873187 [-], 1929392979511hypothetical protein  TssI
8A3UG_133502873284..2873631 [-], 348392979512hypothetical protein 
9A3UG_133552873653..2874708 [-], 1056392979513ADP-ribosyl-[dinitrogen reductase] glycohydrolase 
10A3UG_133602874760..2875041 [-], 282392979514hypothetical protein 
11A3UG_133652875128..2875604 [-], 477392979515hypothetical protein 
12A3UG_133802876416..2877180 [-], 765392979516hypothetical protein 
13A3UG_133852877177..2878643 [-], 1467392979517hypothetical protein 
14A3UG_133902878680..2880113 [-], 1434392979518hypothetical protein 
15A3UG_133952880138..2882753 [-], 2616392979519type VI secretion system protein VasG  TssH
16A3UG_134002882792..2883835 [-], 1044392979520type VI secretion system protein ImpH  TssG
17A3UG_134052883832..2885703 [-], 1872392979521type VI secretion system protein ImpG  TssF
18A3UG_134102885706..2886269 [-], 564392979522type VI secretion system protein ImpF  TssE
19A3UG_134152886262..2887074 [-], 813392979523type VI secretion system protein ImpE  TagJ
20A3UG_134202887084..2888070 [-], 987392979524hypothetical protein 
21A3UG_134252888087..2888884 [-], 798392979525protein serine/threonine phosphatase 
22A3UG_134302888881..2890650 [-], 1770392979526FHA domain-containing protein  Fha
23A3UG_134352890738..2891091 [-], 354392979527hypothetical protein  ECL_01543 (i)
24A3UG_134402891088..2891579 [-], 492392979528putative cytoplasmic protein  ECL_01542 (e)
25A3UG_134452891638..2892120 [-], 483392979529type VI secretion system secreted protein Hcp  TssD
26A3UG_134502892301..2892726 [-], 426392979530hypothetical protein 
27A3UG_134552892723..2893229 [-], 507392979531hypothetical protein 
28A3UG_134602893295..2894794 [-], 1500392979532type VI secretion system protein ImpC  TssC
29A3UG_134652894798..2895322 [-], 525392979533hypothetical protein  TssB
30A3UG_134702895398..2896414 [-], 1017392979534type VI secretion system protein ImpA  TssA
31A3UG_134752896426..2897142 [-], 717392979535type VI secretion system protein ImpM 
32A3UG_134802897159..2900779 [-], 3621392979536type VI secretion system protein ImpL  TssM
33A3UG_134852900782..2902020 [-], 1239392979537hypothetical protein  TssL
34A3UG_134902902038..2903381 [-], 1344392979538type VI secretion system protein ImpJ  TssK
35A3UG_134952903410..2903913 [-], 504392979539type VI secretion system protein VasD  TssJ
36A3UG_135002903937..2904431 [-], 495392979540hypothetical protein 
37A3UG_135052905291..2907579 [+], 2289392979541hypothetical protein 
38A3UG_135102907545..2908336 [-], 792392979542putative ABC phosphate/phosphonate transporter, periplasmic ligand binding protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
EC042_4529 , ECL_03140, EC042_4529, ECL_01567, ECL_01542, SMA2263, EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1A3UG_02355504315..504800 [+], 486392977332type VI secretion system effector EC042_4529
2A3UG_057601263573..1267769 [+], 4197392978007Rhs family protein ECL_03140
3A3UG_116052512938..2513420 [+], 483392979167Hcp family type VI secretion system effector EC042_4529
4A3UG_133102861707..2866098 [-], 4392392979504hypothetical protein ECL_01567
5A3UG_134402891088..2891579 [-], 492392979528putative cytoplasmic protein ECL_01542
6A3UG_134452891638..2892120 [-], 483392979529type VI secretion system secreted protein Hcp SMA2263
7A3UG_142453058632..3059123 [+], 492392979689type VI secretion system effector EC042_4529

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Proteins        Genes

Homology Immunity protein list
ECL_03139, ECL_01543

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1A3UG_057851270905..1271489 [+], 585392978012hypothetical protein ECL_03139
2A3UG_134352890738..2891091 [-], 354392979527hypothetical protein ECL_01543

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Proteins        Genes