I. Summary
SecReT6 ID674 insolico
StrainPseudomonas aeruginosa DK2
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PADK2_0039086144..89242 [-], 3099392981488serine/threonine-protein kinase PpkA  PpkA
2PADK2_0039589250..89978 [-], 729392981489PppA  PppA
3PADK2_0040089988..90668 [-], 681392981490type VI secretion system protein ImpM  TagF
4PADK2_0040590665..94195 [-], 3531392981491hypothetical protein  TssM
5PADK2_0041094192..95541 [-], 1350392981492hypothetical protein  TssL
6PADK2_0041595548..96882 [-], 1335392981493hypothetical protein  TssK
7PADK2_0042096898..97362 [-], 465392981494lipoprotein  TssJ
8PADK2_0042597407..98918 [-], 1512392981495hypothetical protein  Fha
9PADK2_0043099304..100320 [+], 1017392981496hypothetical protein  TssA
10PADK2_00435100409..100927 [+], 519392981497hypothetical protein  TssB
11PADK2_00440100940..102436 [+], 1497392981498hypothetical protein  TssC
12PADK2_00445102512..103000 [+], 489392981499hypothetical protein  TssD
13PADK2_00450103228..104013 [+], 786392981500secretion protein  TagJ
14PADK2_00455104015..104524 [+], 510392981501hypothetical protein  TssE
15PADK2_00460104521..106380 [+], 1860392981502type VI secretion system protein ImpG  TssF
16PADK2_00465106344..107390 [+], 1047392981503hypothetical protein  TssG
17PADK2_00470107383..110091 [+], 2709392981504ClpA/B-type chaperone  TssH
18PADK2_00475110129..112048 [+], 1920392981505hypothetical protein  TssI
19PADK2_00480112163..112447 [-], 285392981506hypothetical protein  Tsi6 (i)
20PADK2_00485112444..113736 [-], 1293392981507hypothetical protein  Tse6 (e)
21PADK2_00490113752..114186 [-], 435392981508hypothetical protein 
22PADK2_00495114440..116665 [+], 2226392981509hypothetical protein  TssI
23PADK2_00500116693..117142 [+], 450392981510hypothetical protein 
24PADK2_00505117159..118271 [+], 1113392981511hypothetical protein 
25PADK2_00510118268..119305 [+], 10383929815123-oxoacyl-(acyl carrier protein) synthase 
26PADK2_00515119305..120465 [+], 1161392981513hypothetical protein  PA0099 (e)
27PADK2_00520120487..121407 [+], 921392981514hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
PA0085 , PA0091, PA0093, PA0095, PA0099, PA3484, PA2774, PA2702, PA2685, PA2684, PA1844

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PADK2_00445102512..103000 [+], 489392981499hypothetical protein PA0085
2PADK2_00475110129..112048 [+], 1920392981505hypothetical protein PA0091
3PADK2_00485112444..113736 [-], 1293392981507hypothetical protein PA0093
4PADK2_00495114440..116665 [+], 2226392981509hypothetical protein PA0095
5PADK2_00515119305..120465 [+], 1161392981513hypothetical protein PA0099
6PADK2_068401488993..1490219 [-], 1227392982776hypothetical protein PA3484
7PADK2_105652262654..2263241 [+], 588392983515hypothetical protein PA2774
8PADK2_111402360898..2361374 [-], 477392983626hypothetical protein PA2702
9PADK2_112202379070..2381139 [+], 2070392983642hypothetical protein PA2685
10PADK2_112252381189..2385142 [+], 3954392983643hypothetical protein PA2684
11PADK2_164353566062..3566526 [+], 465392984681hypothetical protein PA1844

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Proteins        Genes

Homology Immunity protein list
PA0092, PA3485, PA2775, PA2703, Tsi5, PA1845

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PADK2_00480112163..112447 [-], 285392981506hypothetical protein PA0092
2PADK2_068351488559..1488996 [-], 438392982775hypothetical protein PA3485
3PADK2_105602262212..2262649 [+], 438392983514hypothetical protein PA2775
4PADK2_111352360655..2360888 [-], 234392983625hypothetical protein PA2703
5PADK2_112302385139..2385330 [+], 192392983644hypothetical protein Tsi5
6PADK2_164303565502..3566020 [+], 519392984680hypothetical protein PA1845

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Proteins        Genes