I. Summary
SecReT6 ID68 insolico
StrainBurkholderia mallei ATCC 23344
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BMAA0385371884..372831 [-], 94853716359LysR family transcriptional regulator 
2BMAA0387374408..375322 [-], 91577358734LysR family transcriptional regulator 
3BMAA0388375504..376208 [+], 70553716358short chain dehydrogenase/reductase family oxidoreductase 
4BMAA0389376517..377059 [+], 54353716357hypothetical protein 
5BMAA0390376995..377312 [-], 31877358733hypothetical protein 
6BMAA0391377622..378944 [-], 132353716356hypothetical protein 
7BMAA0392379335..381233 [+], 189953716355hypothetical protein 
8BMAA0393381276..382712 [-], 143753716354FHA domain-containing protein  Fha
9BMAA0394382767..383168 [-], 40253716353lipoprotein 
10BMAA0395383354..383638 [+], 28553716352hypothetical protein 
11BMAA0396383787..384326 [+], 54053716351lipoprotein  TssJ
12BMAA0397384323..385726 [+], 140453716350hypothetical protein  TssK
13BMAA0398385742..387058 [+], 131753716349hypothetical protein  TssL
14BMAA0399387061..390690 [+], 363053716348lipoprotein  TssM
15BMAA0400390672..391211 [+], 54077358730hypothetical protein 
16BMAA0400.1391813..394410 [+], 259853717631serine/threonine protein kinase 
17BMAA0402394463..395542 [+], 108053716343hypothetical protein  TssA
18BMAA0403395605..396183 [+], 57977358729hypothetical protein  TssB
19BMAA0404396176..397684 [+], 150977358942hypothetical protein  TssC
20BMAA0405397744..398235 [+], 49277358941hypothetical protein  TssD
21BMAA0406398266..398814 [+], 54977358940hypothetical protein  TssE
22BMAA0407398819..400690 [+], 187277358939hypothetical protein  TssF
23BMAA0408400807..402177 [+], 137177358937hypothetical protein  TssG
24BMAA0409402156..404810 [+], 265553716607ATP-dependent Clp protease, ATP-binding subunit ClpB  TssH
25BMAA0410404807..407011 [+], 220553716606Rhs element Vgr protein  TssI
26BMAA0412407699..408727 [+], 102953716605hypothetical protein 
27BMAA0413408755..409588 [-], 83453716604IS407A, transposase OrfB 
28BMAA0414409612..409875 [-], 26453717424IS407A, transposase OrfA 
29BMAA0415409775..410476 [-], 70277358731hypothetical protein 
30BMAA0416410549..411529 [-], 98153716603hypothetical protein 
31BMAA0417412046..413470 [+], 142553716601cytosine/purines/uracil/thiamine/allantoin permease family protein 
32BMAA0418413467..414405 [+], 93953716602NAD-dependent deacetylase 
33BMAA0419414431..415045 [+], 61553716585hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Schell MA et al. (2007). Type VI secretion is a major virulence determinant in Burkholderia mallei. Mol Microbiol. 64(6):1466-85. [PudMed:17555434] experimental
experimental This literature contains experimental investigation