I. Summary
SecReT6 ID688 insolico
StrainBurkholderia cepacia GG4
Repliconchromosome I [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1GEM_30313311401..3312429 [-], 1029402567776Mg2 transporter protein CorA family protein 
2GEM_30323312638..3313591 [-], 954402567777tail fiber protein 
3GEM_30333313713..3314558 [+], 846402567778peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin 
4GEM_30343314859..3318800 [+], 3942402567779type VI secretion protein IcmF  TssM
5GEM_30353318797..3319786 [+], 990402567780hypothetical protein 
6GEM_30363319791..3320747 [+], 957402567781OmpA/MotB domain-containing protein  TagL
7GEM_30373320825..3321946 [-], 1122402567782type VI secretion-associated protein, ImpA family  TssA
8GEM_30383321986..3324655 [-], 2670402567783type VI secretion ATPase, ClpV1 family  TssH
9GEM_30393324700..3325800 [-], 1101402567784type VI secretion system protein  TssG
10GEM_30403325764..3327599 [-], 1836402567785type VI secretion system protein  TssF
11GEM_30413327677..3328162 [-], 486402567786type VI secretion system protein TssE  TssE
12GEM_30423328225..3328728 [-], 504402567787type VI secretion system protein  TssD
13GEM_30433328799..3330289 [-], 1491402567788type VI secretion protein  TssC
14GEM_30443330305..3330820 [-], 516402567789type VI secretion system protein  TssB
15GEM_30453330865..3331503 [-], 639402567790Tetratricopeptide TPR 2 repeat protein 
16GEM_30463331894..3332493 [+], 600402567791type VI secretion system protein  TssJ
17GEM_30473332596..3333942 [+], 1347402567792type VI secretion system protein  TssK
18GEM_30483333939..3334721 [+], 783402567793transmembrane protein  TssL
19GEM_30493334808..3335125 [-], 318402567794hypothetical protein 
20GEM_30503335465..3336265 [+], 801402567795extracellular solute-binding protein 
21GEM_30513336347..3336550 [-], 204402567796hypothetical protein 
22GEM_30523336869..3337894 [+], 1026402567797XRE family transcriptional regulator 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
BTH_I2693 , BTH_I2697, BTH_I2698, BTH_I2705, BCAL0343

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1GEM_20762264523..2267327 [-], 2805402566842rhs element vgr BTH_I2693
2GEM_20802270338..2274066 [-], 3729402566846rhs element vgr BTH_I2697
3GEM_20812274128..2276527 [-], 2400402566847secreted protein hcp BTH_I2698
4GEM_20842278097..2280892 [-], 2796402566850VgrG protein BTH_I2705
5GEM_30423328225..3328728 [-], 504402567787type VI secretion system protein BCAL0343

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Proteins        Genes