I. Summary
SecReT6 ID71 insolico
StrainBurkholderia mallei ATCC 23344
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BMAA18922071093..2071485 [-], 39377358766AraC family transcriptional regulator 
2BMAA18932071559..2072335 [-], 77753716012quinone family NAD(P)H dehydrogenase 
3BMAA18942072431..2073324 [+], 89453716003LysR family transcriptional regulator 
4BMAA18952073664..2075580 [+], 191753716002hypothetical protein 
5BMAA18962076057..2076164 [-], 10853716001hypothetical protein 
6BMAA18972076300..2076680 [-], 38153716000hypothetical protein 
7BMAA18982076721..2077380 [-], 66053715999hypothetical protein 
8BMAA18992077562..2078644 [-], 108353717601hypothetical protein 
9BMAA19002078641..2081118 [-], 247853715998pentapeptide repeat-containing protein 
10BMAA19012081150..2083477 [-], 232853715997Rhs element Vgr protein  TssI
11BMAA19022083549..2084652 [-], 1104229220803hypothetical protein  TssA
12BMAA19042085733..2087622 [-], 189053715987hypothetical protein  TssF
13BMAA19052087653..2088234 [-], 58277358764hypothetical protein  TssE
14BMAA19062088221..2089186 [-], 96677358763hypothetical protein  TagJ
15BMAA19072089183..2089929 [-], 74753715986hypothetical protein 
16BMAA19092093394..2093975 [+], 58253715985hypothetical protein  TssB
17BMAA19102094010..2095509 [+], 150077358759hypothetical protein  TssC
18BMAA19112095626..2096111 [+], 48677358758hypothetical protein  TssD
19BMAA19122096218..2096721 [+], 50477358757hypothetical protein  TssJ
20BMAA19132096743..2098089 [+], 134777358756hypothetical protein  TssK
21BMAA19142098163..2099443 [+], 128153715977hypothetical protein  TssL
22BMAA19162104079..2104315 [+], 23753715976hypothetical protein 
23BMAA19172104304..2104654 [-], 35177358753hypothetical protein 
24BMAA19182104791..2105729 [+], 93953715975LysR family transcriptional regulator 
25BMAA19192105972..2106898 [-], 92777358752class III extradiol-type catecholic dioxygenase 
26BMAA19202106953..2107924 [-], 97253715967quinone oxidoreductase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Schell MA et al. (2007). Type VI secretion is a major virulence determinant in Burkholderia mallei. Mol Microbiol. 64(6):1466-85. [PudMed:17555434] experimental
experimental This literature contains experimental investigation