I. Summary
SecReT6 ID727 insolico
StrainEnterobacter aerogenes EA1509E
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ST548_p70641249677..1250654 [+], 978444351390putative dehydrogenase 
2ST548_p70631250728..1252050 [-], 1323444351391COG1649 predicted glycoside hydrolase 
3ST548_p70621252293..1252610 [+], 318444351392hypothetical protein 
4ST548_p70611253219..1253713 [+], 495444351393hypothetical protein 
5ST548_p70601253738..1254244 [+], 507444351394Type VI secretion lipoprotein/VasD  TssJ
6ST548_p70591254269..1255612 [+], 1344444351395Uncharacterized protein ImpJ/VasE  TssK
7ST548_p70581255627..1256856 [+], 1230444351396Outer membrane protein ImpK/VasF, OmpA/MotB domain  TssL
8ST548_p70571256859..1260470 [+], 3612444351397IcmF-related protein  TssM
9ST548_p70561260487..1261194 [+], 708444351398Protein phosphatase ImpM 
10ST548_p70551261206..1262216 [+], 1011444351399Uncharacterized protein ImpA  TssA
11ST548_p70541262292..1262816 [+], 525444351400Uncharacterized protein ImpB  TssB
12ST548_p70531262820..1264319 [+], 1500444351401Uncharacterized protein ImpC  TssC
13ST548_p70521264361..1264777 [+], 417444351402Putative inner membrane protein 
14ST548_p70511264774..1265268 [+], 495444351403hypothetical protein 
15ST548_p70501265297..1265719 [+], 423444351404FIG01055876: hypothetical protein 
16ST548_p70491265739..1265870 [-], 132444351405hypothetical protein 
17ST548_p70481265899..1266381 [+], 483444351406Uncharacterized protein ImpD  TssD
18ST548_p70471266554..1268281 [+], 1728444351407Uncharacterized protein ImpI/VasC  Fha
19ST548_p70461268281..1269075 [+], 795444351408Protein serine/threonine phosphatase PrpC, regulation of stationary phase 
20ST548_p70451269097..1270080 [+], 984444351409hypothetical protein 
21ST548_p70441270090..1270884 [+], 795444351410Protein of avirulence locus ImpE  TagJ
22ST548_p70431270881..1271444 [+], 564444351411Uncharacterized protein ImpF  TssE
23ST548_p70421271447..1273318 [+], 1872444351412Protein ImpG/VasA  TssF
24ST548_p70411273315..1274358 [+], 1044444351413Uncharacterized protein ImpH/VasB  TssG
25ST548_p70401274408..1277020 [+], 2613444351414ClpB protein  TssH
26ST548_p70391277045..1278469 [+], 1425444351415Serine/threonine protein kinase 
27ST548_p70381278548..1278937 [+], 390444351416hypothetical protein 
28ST548_p70371278934..1279308 [+], 375444351417hypothetical protein 
29ST548_p70361279347..1281590 [+], 2244444351418VgrG protein  TssI
30ST548_p70351282287..1282451 [+], 165444351419hypothetical protein 
31ST548_p70341282942..1283319 [+], 378444351420hypothetical protein 
32ST548_p70331283353..1283733 [+], 381444351421hypothetical protein 
33ST548_p70321283799..1286339 [+], 2541444351422pentapeptide repeat 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SMA2263 , SMA3455

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ST548_p70481265899..1266381 [+], 483444351406Uncharacterized protein ImpD SMA2263
2ST548_p37244705843..4706325 [+], 483444354730Uncharacterized protein ImpD SMA3455

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Proteins        Genes