I. Summary
SecReT6 ID73 insolico
StrainBurkholderia pseudomallei K96243
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BPSS0164217017..217988 [+], 97253721200quinone oxidoreductase 
2BPSS0165218043..218969 [+], 92753721201dioxygenase 
3BPSS0166219213..220175 [-], 96353721202LysR family transcriptional regulator 
4BPSS0167221397..225473 [-], 407753721203hypothetical protein  TssM
5BPSS0168225502..226767 [-], 126653721204hypothetical protein  TssL
6BPSS0169226856..228202 [-], 134753721205hypothetical protein  TssK
7BPSS0170228224..228736 [-], 51353721206lipoprotein  TssJ
8BPSS0171228834..229319 [-], 48653721207hypothetical protein  TssD
9BPSS0172229436..230935 [-], 150053721208hypothetical protein  TssC
10BPSS0173230970..231551 [-], 58253721209hypothetical protein  TssB
11BPSS0174231587..234526 [-], 294053721210chaperone  TssH
12BPSS0175235059..235778 [+], 72053721211hypothetical protein 
13BPSS0176235775..236740 [+], 96653721212hypothetical protein  TagJ
14BPSS0177236781..237308 [+], 52853721213hypothetical protein  TssE
15BPSS0178237339..239228 [+], 189053721214hypothetical protein  TssF
16BPSS0179239240..240313 [+], 107453721215hypothetical protein  TssG
17BPSS0180240310..241455 [+], 114653721216hypothetical protein  TssA
18BPSS0181241527..243854 [+], 232853721217hypothetical protein  TssI
19BPSS0182243886..246363 [+], 247853721218hypothetical protein 
20BPSS0183246360..247442 [+], 108353721219hypothetical protein 
21BPSS0184247624..248283 [+], 66053721220hypothetical protein 
22BPSS0185248330..248704 [+], 37553721221hypothetical protein 
23BPSS0186249406..251322 [-], 191753721222hypothetical protein 
24BPSS0187251662..252555 [-], 89453721223LysR family transcriptional regulator 
25BPSS0188252651..253427 [+], 77753721224dehydrogenase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Burtnick MN et al. (2011). The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 79(4):1512-25. [PudMed:21300775] experimental
experimental This literature contains experimental investigation