I. Summary

SecReT6 ID	73
Strain	Burkholderia pseudomallei K96243
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_006351
Location	221397..248704
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BPSS0164	217017..217988 [+], 972	53721200	quinone oxidoreductase
2	BPSS0165	218043..218969 [+], 927	53721201	dioxygenase
3	BPSS0166	219213..220175 [-], 963	53721202	LysR family transcriptional regulator
4	BPSS0167	221397..225473 [-], 4077	53721203	hypothetical protein	TssM
5	BPSS0168	225502..226767 [-], 1266	53721204	hypothetical protein	TssL
6	BPSS0169	226856..228202 [-], 1347	53721205	hypothetical protein	TssK
7	BPSS0170	228224..228736 [-], 513	53721206	lipoprotein	TssJ
8	BPSS0171	228834..229319 [-], 486	53721207	hypothetical protein	TssD
9	BPSS0172	229436..230935 [-], 1500	53721208	hypothetical protein	TssC
10	BPSS0173	230970..231551 [-], 582	53721209	hypothetical protein	TssB
11	BPSS0174	231587..234526 [-], 2940	53721210	chaperone	TssH
12	BPSS0175	235059..235778 [+], 720	53721211	hypothetical protein
13	BPSS0176	235775..236740 [+], 966	53721212	hypothetical protein	TagJ
14	BPSS0177	236781..237308 [+], 528	53721213	hypothetical protein	TssE
15	BPSS0178	237339..239228 [+], 1890	53721214	hypothetical protein	TssF
16	BPSS0179	239240..240313 [+], 1074	53721215	hypothetical protein	TssG
17	BPSS0180	240310..241455 [+], 1146	53721216	hypothetical protein	TssA
18	BPSS0181	241527..243854 [+], 2328	53721217	hypothetical protein	TssI
19	BPSS0182	243886..246363 [+], 2478	53721218	hypothetical protein
20	BPSS0183	246360..247442 [+], 1083	53721219	hypothetical protein
21	BPSS0184	247624..248283 [+], 660	53721220	hypothetical protein
22	BPSS0185	248330..248704 [+], 375	53721221	hypothetical protein
23	BPSS0186	249406..251322 [-], 1917	53721222	hypothetical protein
24	BPSS0187	251662..252555 [-], 894	53721223	LysR family transcriptional regulator
25	BPSS0188	252651..253427 [+], 777	53721224	dehydrogenase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

N/A

N/A

(1) Burtnick MN et al. (2011). The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 79(4):1512-25. [PudMed:21300775]

This literature contains experimental investigation