I. Summary
SecReT6 ID730 insolico
StrainSerratia marcescens WW4
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SMWW4_v1c29950 (cnu)3231299..3231514 [+], 216448242755oriC-binding complex H-NS/Cnu 
2SMWW4_v1c29960 (uspC)3231712..3232131 [+], 420448242756universal stress protein 
3SMWW4_v1c29970 (curA)3232216..3233247 [+], 1032448242757curcumin/dihydrocurcumin reductase, NADPH-dependent 
4SMWW4_v1c299803233282..3233929 [-], 648448242758pyrrolidone-carboxylate peptidase 
5SMWW4_v1c299903234027..3234959 [+], 933448242759LysR family transcriptional regulator 
6SMWW4_v1c300003235473..3237812 [+], 2340448242760Rhs element Vgr protein  TssI
7SMWW4_v1c300103237823..3238212 [+], 390448242761hypothetical protein 
8SMWW4_v1c300203238314..3238814 [+], 501448242762hypothetical protein 
9SMWW4_v1c300303238986..3241538 [+], 2553448242763hypothetical protein 
10SMWW4_v1c300403241535..3242602 [+], 1068448242764hypothetical protein 
11SMWW4_v1c300503242633..3243268 [+], 636448242765hypothetical protein 
12SMWW4_v1c300603243284..3243676 [+], 393448242766hypothetical protein 
13SMWW4_v1c300703243725..3244225 [+], 501448242767hypothetical protein 
14SMWW4_v1c30080 (vasD)3244255..3244785 [+], 531448242768type VI secretion system protein VasD  TssJ
15SMWW4_v1c30090 (impJ)3244826..3246172 [+], 1347448242769type VI secretion system protein ImpJ  TssK
16SMWW4_v1c30100 (impK)3246194..3247396 [+], 1203448242770type VI secretion system protein ImpK  TssL
17SMWW4_v1c30110 (impL)3247396..3251031 [+], 3636448242771type VI secretion system protein ImpL  TssM
18SMWW4_v1c30120 (impM)3251050..3251769 [+], 720448242772type VI secretion system protein ImpM 
19SMWW4_v1c30130 (impA)3251793..3252824 [+], 1032448242773type VI secretion system protein ImpA  TssA
20SMWW4_v1c30140 (impB)3252947..3253483 [+], 537448242774type VI secretion system protein ImpB  TssB
21SMWW4_v1c30150 (impC)3253487..3254992 [+], 1506448242775type VI secretion system protein ImpC  TssC
22SMWW4_v1c301603255297..3255779 [+], 483448242776type VI secretion system secreted protein Hcp  TssD
23SMWW4_v1c301703255850..3256677 [+], 828448242777hypothetical protein 
24SMWW4_v1c301803256691..3257485 [+], 795448242778hypothetical protein 
25SMWW4_v1c301903257463..3257837 [+], 375448242779type VI secretion system-associated protein  Rap2a (i)
26SMWW4_v1c302003257900..3258661 [+], 762448242780hypothetical protein 
27SMWW4_v1c302103258658..3259020 [+], 363448242781hypothetical protein 
28SMWW4_v1c302203259191..3260924 [+], 1734448242782type VI secretion system, FHA domain-containing protein  Fha
29SMWW4_v1c302303260924..3261697 [+], 774448242783protein serine/threonine phosphatase 
30SMWW4_v1c302403261726..3262712 [+], 987448242784putative type VI secretion system-associated protein 
31SMWW4_v1c30250 (cciE)3262728..3263549 [+], 822448242785virulence protein SciE  TagJ
32SMWW4_v1c30260 (impF)3263552..3264127 [+], 576448242786type VI secretion system protein ImpF  TssE
33SMWW4_v1c30270 (impG)3264132..3266018 [+], 1887448242787type VI secretion system protein ImpG  TssF
34SMWW4_v1c30280 (impH)3266015..3267085 [+], 1071448242788type VI secretion system protein ImpH  TssG
35SMWW4_v1c30290 (vasG)3267142..3269799 [+], 2658448242789type VI secretion system protein VasG  TssH
36SMWW4_v1c303003269849..3271294 [+], 1446448242790serine/threonine protein kinase 
37SMWW4_v1c303103271436..3273364 [+], 1929448242791Rhs element Vgr protein  TssI
38SMWW4_v1c30320 (sbmC)3273552..3274019 [-], 468448242792DNA gyrase inhibitor 
39SMWW4_v1c303303274042..3274884 [-], 843448242793tryptophan 2,3-dioxygenase 
40SMWW4_v1c303403275180..3276217 [+], 1038448242794LacI family transcriptional regulator 
41SMWW4_v1c303503276413..3277723 [+], 1311448242795major facilitator superfamily transporter 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SMA1112 , SMA2244, SMA2263, SMA2276

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SMWW4_v1c180201987979..1988530 [+], 552448241572hypothetical protein SMA1112
2SMWW4_v1c300003235473..3237812 [+], 2340448242760Rhs element Vgr protein SMA2244
3SMWW4_v1c301603255297..3255779 [+], 483448242776type VI secretion system secreted protein Hcp SMA2263
4SMWW4_v1c303103271436..3273364 [+], 1929448242791Rhs element Vgr protein SMA2276

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Proteins        Genes

Homology Immunity protein list
SMA1111, SMA2265

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SMWW4_v1c180101987732..1988013 [+], 282448241571hypothetical protein SMA1111
2SMWW4_v1c301903257463..3257837 [+], 375448242779type VI secretion system-associated protein SMA2265

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Proteins        Genes