SecReT6
I. Summary
SecReT6 ID752 insolico
StrainEnterobacter cloacae subsp. cloacae NCTC 9394
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_021046
Location935277..962988
Comment
FunctionN/A
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1010
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ENC_08860930787..931752 [+], 966479271620L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily 
2ENC_08870931743..932456 [-], 714479271621Predicted carboxypeptidase 
3ENC_08900935277..935768 [+], 492479271622type VI secretion protein, VC_A0107 family  TssB
4ENC_08910935803..937344 [+], 1542479271623type VI secretion protein, EvpB/VC_A0108 family  TssC
5ENC_08920937360..938700 [+], 1341479271624type VI secretion protein, VC_A0114 family  TssK
6ENC_08930938697..939386 [+], 690479271625type IV / VI secretion system protein, DotU family  TssL
7ENC_08940939383..941089 [+], 1707479271626Outer membrane protein and related peptidoglycan-associated (lipo)proteins  TagL
8ENC_08950941095..941586 [+], 492479271627type VI secretion system effector, Hcp1 family  TssD
9ENC_08960941760..944405 [+], 2646479271628type VI secretion ATPase, ClpV1 family  TssH
10ENC_08970944402..946894 [+], 2493479271629type VI secretion system Vgr family protein  TssI
11ENC_08980947632..947796 [+], 165479271630hypothetical protein 
12ENC_09000950888..951283 [+], 396479271631hypothetical protein 
13ENC_09010951313..952044 [+], 732479271632Protein of unknown function (DUF3274). 
14ENC_09020952396..953826 [+], 1431479271633hypothetical protein 
15ENC_09050957564..959165 [+], 1602479271634type VI secretion-associated protein, VC_A0119 family  TssA
16ENC_09060959207..960961 [+], 1755479271635type VI secretion protein, VC_A0110 family  TssF
17ENC_09070960925..962010 [+], 1086479271636type VI secretion protein, VC_A0111 family  TssG
18ENC_09090962533..962988 [+], 456479271637type VI secretion system lysozyme-related protein  TssE
19ENC_09120964705..965193 [+], 489479271638hypothetical protein 
20ENC_09130965491..965706 [+], 216479271639hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
EC042_4529 , EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ENC_08950941095..941586 [+], 492479271627type VI secretion system effector, Hcp1 family EC042_4529
2ENC_311903152480..3152971 [+], 492479273322type VI secretion system effector, Hcp1 family EC042_4529

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Proteins        Genes
N/A
N/A