SecReT6
I. Summary
SecReT6 ID758 insolico
StrainBurkholderia thailandensis MSMB121
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_021173
Location522577..542553
Comment
FunctionN/A
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111011111
ComponentTssGTssJTssKTssM
Number1111
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BTI_483518359..519627 [+], 1269488604569divergent AAA domain protein 
2BTI_484520406..520744 [-], 339488602810hypothetical protein 
3BTI_485 (higA)520903..522036 [-], 1134488605222addiction module antidote protein, HigA family 
4BTI_486 (nit)522076..522378 [+], 303488604683nitrilase domain protein 
5BTI_487522577..523362 [-], 786488604080type IV/VI secretion system, DotU family domain protein  TssL
6BTI_488523359..524705 [-], 1347488605200hypothetical protein  TssK
7BTI_489524814..525428 [-], 615488602370type VI secretion lipofamily protein  TssJ
8BTI_490525802..526467 [+], 666488603904tetratricopeptide repeat family protein 
9BTI_491526504..527022 [+], 519488605096hypothetical protein  TssB
10BTI_492527040..528530 [+], 1491488604462hypothetical protein  TssC
11BTI_493528603..529106 [+], 504488603078type VI secretion system effector, Hcp1 family protein  TssD
12BTI_494529158..529640 [+], 483488603968lysozyme family protein  TssE
13BTI_495529720..531558 [+], 1839488602274hypothetical protein  TssF
14BTI_496531522..532622 [+], 1101488604198hypothetical protein  TssG
15BTI_497 (clpV)532656..535325 [+], 2670488604345type VI secretion ATPase, ClpV1 family  TssH
16BTI_498535411..536541 [+], 1131488603355impA-related N-terminal family protein  TssA
17BTI_499536719..537660 [-], 942488603483ompA family protein  TagL
18BTI_500537665..538654 [-], 990488603400hypothetical protein 
19BTI_501538651..542553 [-], 3903488604310intracellular multiplication and macrophage-killing family protein  TssM
20BTI_502542846..543493 [-], 648488604781D-alanyl-D-alanine carboxypeptidase family protein 
21BTI_503543823..544842 [+], 1020488604646hypothetical protein 
22BTI_504545013..546461 [-], 1449488604651outer membrane efflux family protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BCAL0343 , BTH_I3225, BTH_I0068, BTH_II0310

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BTI_493528603..529106 [+], 504488603078type VI secretion system effector, Hcp1 family protein BCAL0343
2BTI_27733056143..3058926 [-], 2784488603274Rhs element Vgr family protein BTH_I3225
3BTI_5975134..75574 [-], 441488604541hypothetical protein BTH_I0068
4BTI_49741710765..1711670 [-], 906488606046D-mannose binding lectin family protein BTH_II0310

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Proteins        Genes

Homology Immunity protein list
BTH_I0069

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BTI_5874782..75147 [-], 366488602965putative lipoprotein BTH_I0069

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Proteins        Genes
N/A

Genomics & Bioinformatics Group in MML, SJTU