I. Summary
SecReT6 ID767 insolico
StrainSalmonella enterica subsp. enterica serovar Weltevreden str. 2007-60-3289-1
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SENTW_0221 (dniR)5319..6686 [-], 1368409248681transcriptional regulator for nitrite reductase (cytochrome c552) 
2SENTW_0222 (gloB)6758..7513 [-], 756409248682probable hydroxyacylglutathione hydrolase 
3SENTW_0223 (yafS)7548..8270 [+], 723409248683Uncharacterized protein yafS 
4SENTW_0224 (rnhA)8267..8734 [-], 468409248684RNase HI, degrades RNA of DNA-RNA hybrids 
5SENTW_0225 (dnaQ)8789..9529 [+], 741409248685DNA polymerase III epsilon subunit 
6SENTW_0226 (safA)10058..11113 [-], 1056409248686putative cytoplasmic protein  TssA
7SENTW_0227 (sciB)11124..12119 [-], 996409248687hypothetical protein  TssG
8SENTW_0228 (safC)12116..13999 [-], 1884409248688hypothetical protein  TssF
9SENTW_0229 (sciD)14015..14509 [-], 495409248689hypothetical protein  TssE
10SENTW_0230 (sat1)14506..15345 [-], 840409248690hypothetical protein  TagJ
11SENTW_0231 (sat2)15317..16219 [-], 903409248691putative cytoplasmic protein 
12SENTW_0232 (clpB)16587..19226 [+], 2640409248692Chaperone protein clpB  TssH
13SENTW_023319326..19868 [+], 543409248693hypothetical protein  TssB
14SENTW_0234 (sirA)19892..21400 [+], 1509409248694hypothetical protein  TssC
15SENTW_023521453..21854 [+], 402409248695hypothetical protein  STY0300 (e)
16SENTW_023621826..22251 [+], 426409248696hypothetical protein  STY0301 (i)
17SENTW_023722188..22295 [-], 108409248697hypothetical protein 
18SENTW_0238 (sciK1)22488..22973 [+], 486409248698Protein hcp1  TssD
19SENTW_023923277..23762 [+], 486409248699putative cytoplasmic protein  STM0277 (e)
20SENTW_024023747..24130 [+], 384409248700putative periplasmic protein  STM0278 (i)
21SENTW_0241 (sciK3)24273..24758 [+], 486409248701Protein hcp1  TssD
22SENTW_024224825..25361 [+], 537409248702hypothetical protein  TssJ
23SENTW_0243 (sciO)25365..26708 [+], 1344409248703hypothetical protein  TssK
24SENTW_0244 (ytxE)26705..28009 [+], 1305409248704Uncharacterized 24.6 kDa protein in ccpA 3'region ORF2  TssL
25SENTW_0245 (sciQ)28014..28787 [+], 774409248705hypothetical protein 
26SENTW_0246 (sciR)28978..29421 [+], 444409248706putative shiga-like toxin A subunit 
27SENTW_0247 (sciS)29455..33324 [+], 3870409248707hypothetical protein  TssM
28SENTW_0248 (sciT)33324..34091 [+], 768409248708hypothetical protein 
29SENTW_024934589..35062 [+], 474409248709probable secreted protein 
30SENTW_025035620..36081 [+], 462409248710probable secreted protein 
31SENTW_025136090..36197 [+], 108409248711hypothetical protein 
32SENTW_025236166..36909 [+], 744409248712hypothetical protein 
33SENTW_0253 (rhsG)37404..39605 [+], 2202409248713Rhs-family protein  TssI
34SENTW_025439629..40075 [+], 447409248714hypothetical protein 
35SENTW_0255 (rhsD1)40094..44182 [+], 4089409248715Protein rhsA  PAAR
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
STY0300 , SciK, STM0277, SciK

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SENTW_023521453..21854 [+], 402409248695hypothetical protein STY0300
2SENTW_0238(sciK1)22488..22973 [+], 486409248698Protein hcp1 SciK
3SENTW_023923277..23762 [+], 486409248699putative cytoplasmic protein STM0277
4SENTW_0241(sciK3)24273..24758 [+], 486409248701Protein hcp1 SciK

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Proteins        Genes

Homology Immunity protein list
STY0301, STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SENTW_023621826..22251 [+], 426409248696hypothetical protein STY0301
2SENTW_024023747..24130 [+], 384409248700putative periplasmic protein STM0278
3SENTW_2500958..1476 [+], 519409250981putative lipoprotein STY2607

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Proteins        Genes
(1) Brankatschk K et al. (2012). Comparative genomic analysis of Salmonella enterica subsp. enterica serovar Weltevreden foodborne strains with other serovars. Int J Food Microbiol. 155(3):247-56. [PudMed:22341936] in_silico
in_silico This literature contains bioinformatics investigation