• T6SS
• Effector
• Immunity
• Reference

I. Summary

SecReT6 ID	769
Strain	Francisella tularensis TIGB03
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_016933
Location	1455732..1480847
Comment
Function	N/A
T6SS Type	Type ii (Type FPI)
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	PdpA	PdpB	IglE	VgrG	IglF	IglG	IglH	DotU	IglI
Number	1	1	1	1	1	1	1	1	1
Component	IglJ	PdpC	PdpE	IglD	IglC	IglB	IglA	PdpD
Number	1	1	1	1	1	1	1	1

17

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	FTU_1369	1455732..1458194 [+], 2463	379717633	hypothetical protein	PdpA
2	FTU_1370	1458199..1461480 [+], 3282	379717634	hypothetical protein	PdpB
3	FTU_1371	1461470..1461847 [+], 378	379717635	hypothetical protein	IglE
4	FTU_1372	1461860..1462354 [+], 495	379717636	hypothetical protein	VgrG
5	FTU_1373	1462359..1464089 [+], 1731	379717637	DNA polymerase I	IglF
6	FTU_1374	1464090..1464611 [+], 522	379717638	hypothetical protein	IglG
7	FTU_1375	1464624..1466054 [+], 1431	379717639	hypothetical protein	IglH
8	FTU_1376	1466067..1466690 [+], 624	379717640	hypothetical protein	DotU
9	FTU_1377	1466712..1467863 [+], 1152	379717641	hypothetical protein	IglI
10	FTU_1378	1467886..1468602 [+], 717	379717642	hypothetical protein	IglJ
11	FTU_1379 (pdpC1)	1468642..1472628 [+], 3987	379717643	Pathogenicity determinant protein C	PdpC
12	FTU_1380	1472646..1473221 [+], 576	379717644	hypothetical protein	PdpE
13	FTU_1381 (iglD1)	1473228..1474424 [-], 1197	379717645	Intracellular growth locus subunit D	IglD
14	FTU_1382 (iglC1)	1474445..1475074 [-], 630	379717646	Intracellular growth locus subunit C	IglC
15	FTU_1383 (iglB1)	1475091..1476611 [-], 1521	379717647	hypothetical protein	IglB
16	FTU_1384 (iglA1)	1476625..1477179 [-], 555	379717648	hypothetical protein	IglA
17	FTU_1385 (pdpD1)	1477260..1480847 [-], 3588	379717649	Pathogenicity determinant protein D	PdpD

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

FTT_1347 , FTL_0118

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	FTU_1372	1461860..1462354 [+], 495	379717636	hypothetical protein	FTT_1347
2	FTU_1377	1466712..1467863 [+], 1152	379717641	hypothetical protein	FTL_0118

Download FASTA format files

Proteins        Genes

N/A

N/A

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