I. Summary

SecReT6 ID	774
Strain	Francisella cf. novicida Fx1
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_017450
Location	1377738..1403171
Comment
Function	N/A
T6SS Type	Type ii (Type FPI)
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	PdpA	PdpB	IglE	VgrG	IglF	IglG	IglH	DotU	IglI
Number	1	1	1	1	1	1	1	1	1
Component	IglJ	PdpC	PdpE	IglD	IglC	IglB	IglA	PdpD
Number	1	1	1	1	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	FNFX1_1347	1377738..1380200 [+], 2463	385793279	hypothetical protein	PdpA
2	FNFX1_1348	1380205..1383486 [+], 3282	385793280	hypothetical protein	PdpB
3	FNFX1_1349	1383554..1383853 [+], 300	385793281	hypothetical protein	IglE
4	FNFX1_1350	1383866..1384360 [+], 495	385793282	hypothetical protein	VgrG
5	FNFX1_1351	1384365..1386095 [+], 1731	385793283	hypothetical protein	IglF
6	FNFX1_1352	1386096..1386617 [+], 522	385793284	hypothetical protein	IglG
7	FNFX1_1353	1386630..1388060 [+], 1431	385793285	hypothetical protein	IglH
8	FNFX1_1354	1388073..1388696 [+], 624	385793286	hypothetical protein	DotU
9	FNFX1_1355	1388718..1389869 [+], 1152	385793287	hypothetical protein	IglI
10	FNFX1_1356	1389892..1390608 [+], 717	385793288	hypothetical protein	IglJ
11	FNFX1_1357	1390648..1394625 [+], 3978	385793289	hypothetical protein	PdpC
12	FNFX1_1358	1394643..1395218 [+], 576	385793290	hypothetical protein	PdpE
13	FNFX1_1359	1395401..1396597 [-], 1197	385793291	hypothetical protein	IglD
14	FNFX1_1360	1396618..1397247 [-], 630	385793292	hypothetical protein	IglC
15	FNFX1_1361	1397265..1398785 [-], 1521	385793293	hypothetical protein	IglB
16	FNFX1_1362	1398799..1399353 [-], 555	385793294	hypothetical protein	IglA
17	FNFX1_1363	1399434..1403171 [-], 3738	385793295	hypothetical protein	PdpD
18	FNFX1_1364	1403272..1404387 [-], 1116	385793296	hypothetical protein
19	FNFX1_1365	1404552..1405760 [+], 1209	385793297	hypothetical protein
20	FNFX1_1366	1405762..1407216 [+], 1455	385793298	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

FTN_1312 , FTL_0118

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	FNFX1_1350	1383866..1384360 [+], 495	385793282	hypothetical protein	FTN_1312
2	FNFX1_1355	1388718..1389869 [+], 1152	385793287	hypothetical protein	FTL_0118

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Proteins        Genes

N/A

N/A