I. Summary
SecReT6 ID778 insolico
StrainFrancisella tularensis subsp. holarctica F92
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType ii (Type FPI)
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1F92_0056598132..98416 [-], 285423049846hypothetical protein 
2F92_0057098419..98829 [-], 411423049847hypothetical protein 
3F92_0057598850..99242 [-], 393423049848lipoprotein 
4F92_0058099414..100019 [+], 606423049849nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein 
5F92_00585100043..100423 [+], 381423049850transposase 
6F92_00590100411..100923 [+], 513423049851transposase ISFtu1 
7F92_00595100924..101796 [-], 873423049852hypothetical protein 
8F92_00610102584..103138 [+], 555423049853intracellular growth locus subunit A  IglA
9F92_00615103152..104672 [+], 1521423049854intracellular growth locus BII  IglB
10F92_00620104683..105318 [+], 636423049855intracellular growth locus CII  IglC
11F92_00625105339..106535 [+], 1197423049856intracellular growth locus DII  IglD
12F92_00630106542..107117 [-], 576423049857hypothetical protein  PdpE
13F92_00635107135..111121 [-], 3987423049858pathogenicity determinant protein PdpC  PdpC
14F92_00640111161..111934 [-], 774423049859hypothetical protein  IglJ
15F92_00645111900..113051 [-], 1152423049860hypothetical protein  IglI
16F92_00650113073..113696 [-], 624423049861developmental protein, putative  DotU
17F92_00665115150..115671 [-], 522423049862hypothetical protein  IglG
18F92_00670115672..117402 [-], 1731423049863hypothetical protein  IglF
19F92_00675117407..117901 [-], 495423049864hypothetical protein  VgrG
20F92_00680117914..118291 [-], 378423049865lipoprotein  IglE
21F92_00685118281..121562 [-], 3282423049866pathogenicity deteminant protein PdpB  PdpB
22F92_00690121567..124029 [-], 2463423049867pathogenicity deteminant protein PdpA  PdpA
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
FTL_0118 , FTT_1347

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1F92_00645111900..113051 [-], 1152423049860hypothetical protein FTL_0118
2F92_00675117407..117901 [-], 495423049864hypothetical protein FTT_1347

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Proteins        Genes