I. Summary
SecReT6 ID8 insolico
StrainEscherichia coli O157:H7 str. Sakai
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECs0205234451..235251 [+], 80115829459hypothetical protein 
2ECs0206235329..236099 [+], 77115829460biotin synthesis protein 
3ECs0207 (mltD)236147..237505 [-], 135915829461membrane-bound lytic murein transglycosylase D 
4ECs0208237577..238332 [-], 75615829462hydroxyacylglutathione hydrolase 
5ECs0209238348..239088 [+], 74115829463hypothetical protein 
6ECs0210 (rnhA)239085..239552 [-], 46815829464ribonuclease H 
7ECs0211239617..240348 [+], 73215829465DNA polymerase III subunit epsilon 
8ECs0212241871..242167 [-], 29715829466hypothetical protein 
9ECs0213242164..242613 [-], 45015829467hypothetical protein 
10ECs0214242616..243263 [-], 64815829468hypothetical protein 
11ECs0216243533..244012 [-], 48015829470Hcp-like protein  TssD
12ECs0217243978..245387 [-], 141015829471hypothetical protein  TssA
13ECs0218245398..248505 [-], 310815829472IcmF-like protein  TssM
14ECs0220248969..249763 [-], 79515829474hypothetical protein  TssA
15ECs0221249760..250380 [-], 62115829475hypothetical protein 
16ECs0222250385..251128 [-], 74415829476hypothetical protein 
17ECs0223251125..253896 [-], 277215829477ATP-dependent Clp proteinase ATP-binding chain  TssH
18ECs0224253905..254666 [-], 76215829478hypothetical protein  TssL
19ECs0225254671..256002 [-], 133215829479hypothetical protein  TssK
20ECs0226256005..256529 [-], 52515829480lipoprotein  TssJ
21ECs0227256526..257806 [-], 128115829481hypothetical protein  Fha
22ECs0228257831..258913 [-], 108315829482hypothetical protein  TssG
23ECs0229258877..260727 [-], 185115829483hypothetical protein  TssF
24ECs0230260731..261144 [-], 41415829484hypothetical protein  TssE
25ECs0231261235..262626 [-], 139215829485hypothetical protein  TssC
26ECs0232262677..262901 [-], 22515829486hypothetical protein 
27ECs0233262936..263436 [-], 50115829487hypothetical protein  TssB
28ECs0234264133..264651 [+], 51915829488hypothetical protein  TssD
29ECs0235264684..264821 [+], 13815829489hypothetical protein 
30ECs0236264861..267002 [+], 214215829490protein VgrG  TssI
31ECs0237267078..271292 [+], 421515829491RhsG core protein with extension  PAAR
32ECs0238271295..271906 [+], 61215829492hypothetical protein 
33ECs0239271928..272110 [+], 18315829493hypothetical protein 
34ECs0240272254..272544 [+], 29115829494hypothetical protein 
35ECs0241272652..273788 [+], 113715829495H repeat-containing protein 
36ECs0242273791..275551 [+], 176115829496Rhs core protein 
37ECs0243275535..275705 [+], 17115829497hypothetical protein 
38ECs0244275753..276016 [+], 26415829498hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECs0234264133..264651 [+], 51915829488hypothetical protein ECA4275

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Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation