SecReT6 ID	802
Strain	Vibrio anguillarum NB10
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	GQ118992
Location	1..11619
Comment	Type VI secretion modulates quorum sensing and stress response in Vibrio anguillarum.
Function	effector translocation
Experimental investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	0	1	0	0	0	0	0	0
Component	TssG	TssJ	TssK	TssM
Number	0	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	clpV (clpV)	1..591 [+], 591	239509131	ClpV	TssH
2	vtsA (vtsA)	734..1888 [+], 1155	239509132	VtsA
3	vtsB (vtsB)	1898..4093 [+], 2196	239509133	VtsB
4	vtsC (vtsC)	4090..5223 [+], 1134	239509134	VtsC
5	vtsD (vtsD)	5226..5921 [+], 696	239509135	VtsD
6	vtsE (vtsE)	5955..6902 [+], 948	239509136	VtsE	Fha
7	vtsF (vtsF)	6902..7369 [+], 468	239509137	VtsF	TssJ
8	vtsG (vtsG)	7369..8685 [+], 1317	239509138	VtsG	TssK
9	vtsH (vtsH)	8693..9835 [+], 1143	239509139	VtsH	TssL
10	vtsI (vtsI)	9837..11619 [+], 1783	239509140	VtsI	TssM

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

Hcp (CDQ49280)

Homology effector (effector protein label, when available)

Homology immunity protein (immunity protein label, when available)

Regulatory element identified

VanT

Regulator	Description	Reference
VanT	Repressor	PMID: 19624706

RpoS

Regulator	Description	Reference
RpoS	Repressor	PMID: 19624706

(1) Weber B et al. (2011). The phosphotransferase VanU represses expression of four qrr genes antagonizing VanO-mediated quorum-sensing regulation in Vibrio anguillarum. Microbiology. 157(Pt 12):3324-39. [PudMed:21948044]

(2) Weber B et al. (2009). Type VI secretion modulates quorum sensing and stress response in Vibrio anguillarum. Environ Microbiol. 11(12):3018-28. [PudMed:19624706]

This literature contains experimental investigation