I. Summary
SecReT6 ID821 insolico
StrainSalmonella enterica subsp. enterica serovar Heidelberg str. CFSAN002069
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1CFSAN002069_07845 (mltD)785850..787217 [-], 1368525827709membrane protein 
2CFSAN002069_07840787289..788044 [-], 756525827708hydroxyacylglutathione hydrolase 
3CFSAN002069_07835788079..788801 [+], 723525827707hypothetical protein 
4CFSAN002069_07830788798..789265 [-], 468525827706ribonuclease H 
5CFSAN002069_07825789329..790060 [+], 732559997021DNA polymerase III subunit epsilon 
6CFSAN002069_07815790592..791647 [-], 1056525827704hypothetical protein  TssA
7CFSAN002069_07810791658..792653 [-], 996525827703SPI-6 associated protein  TssG
8CFSAN002069_07805792650..794533 [-], 1884525830374type VI secretion protein  TssF
9CFSAN002069_07800794549..795043 [-], 495525827702cytoplasmic protein  TssE
10CFSAN002069_07795795040..795864 [-], 825525827701hypothetical protein  TagJ
11CFSAN002069_07790795851..796753 [-], 903525827700hypothetical protein 
12CFSAN002069_07785797121..799760 [+], 2640525827699molecular chaperone  TssH
13CFSAN002069_07780799860..800402 [+], 543525827698type VI secretion protein  TssB
14CFSAN002069_07775800426..801934 [+], 1509525827697EvpB family type VI secretion protein  TssC
15CFSAN002069_07770801987..802388 [+], 402525830373hypothetical protein  STY0300 (e)
16CFSAN002069_07765802360..802785 [+], 426525830372hypothetical protein  STY0301 (i)
17CFSAN002069_07760803022..803507 [+], 486525827696Hcp1 family type VI secretion system effector  TssD
18CFSAN002069_07755803810..804295 [+], 486525827695hypothetical protein  STM0277 (e)
19CFSAN002069_07750804280..804663 [+], 384525827694hypothetical protein  STM0278 (i)
20CFSAN002069_07745804806..805291 [+], 486525827693Hcp1 family type VI secretion system effector  TssD
21CFSAN002069_07740805359..805895 [+], 537559997022outer membrane lipoprotein  TssJ
22CFSAN002069_07735805899..807242 [+], 1344525827691type VI secretion protein  TssK
23CFSAN002069_07730807239..808543 [+], 1305525827690membrane protein  TssL
24CFSAN002069_07725808548..809321 [+], 774525830371membrane protein 
25CFSAN002069_07720809524..809955 [+], 432559997023Shiga toxin A subunit 
26CFSAN002069_07715809989..813858 [+], 3870525827688membrane protein  TssM
27CFSAN002069_07710813858..814625 [+], 768525827687hypothetical protein 
28CFSAN002069_07705814668..815138 [+], 471525830370hypothetical protein 
29CFSAN002069_23995815123..815584 [+], 462559997024hypothetical protein 
30CFSAN002069_24000815593..815715 [+], 123559997025hypothetical protein 
31CFSAN002069_07700815712..816128 [+], 417559997026hypothetical protein 
32CFSAN002069_07695816155..816673 [+], 519525830368SPI-6 associated protein 
33CFSAN002069_07690817070..819301 [+], 2232525827686type VI secretion protein Vgr  TssI
34CFSAN002069_07685819361..819819 [+], 459525830367hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
EvpC , STM0277, EvpC, ROD_34191, STY0300, STY2606

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1CFSAN002069_07745804806..805291 [+], 486525827693Hcp1 family type VI secretion system effector EvpC
2CFSAN002069_07755803810..804295 [+], 486525827695hypothetical protein STM0277
3CFSAN002069_07760803022..803507 [+], 486525827696Hcp1 family type VI secretion system effector EvpC
4CFSAN002069_164903714779..3715264 [-], 486525829058hypothetical protein ROD_34191
5CFSAN002069_07770801987..802388 [+], 402525830373hypothetical protein STY0300
6CFSAN002069_199702964377..2964745 [+], 369525830818hypothetical protein STY2606

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Proteins        Genes

Homology Immunity protein list
STM0278, STY2607, STY0301

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1CFSAN002069_07750804280..804663 [+], 384525827694hypothetical protein STM0278
2CFSAN002069_199652964745..2965263 [+], 519525829595hypothetical protein STY2607
3CFSAN002069_07765802360..802785 [+], 426525830372hypothetical protein STY0301

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Proteins        Genes