I. Summary
SecReT6 ID830 insolico
StrainBurkholderia pseudomallei MSHR305
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BDL_48011641575..1642600 [+], 1026526457533N-acetylmuramoyl-L-alanine amidase family protein 
2BDL_4802 (tibC)1642728..1644128 [+], 1401526458324glycosyltransferase tibC 
3BDL_48031644256..1645746 [+], 1491526459290coiled stalk of trimeric autotransporter adhesin family protein 
4BDL_48041645826..1646203 [+], 378526457091putative lipoprotein 
5BDL_48051646460..1648313 [-], 1854526457372hypothetical protein  TssA
6BDL_48061648304..1649041 [-], 738526457905hypothetical protein  VirG
7BDL_48071649038..1650882 [-], 1845526457093histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein  VirA
8BDL_48081651142..1651636 [+], 495526457335hypothetical protein  TssB
9BDL_48091651633..1653159 [+], 1527526457573hypothetical protein  TssC
10BDL_48101653379..1653888 [+], 510526456830type VI secretion system effector, Hcp1 family protein  TssD
11BDL_48111653881..1654342 [+], 462526456985lysozyme family protein  TssE
12BDL_48121654379..1656121 [+], 1743526458893hypothetical protein  TssF
13BDL_48131656109..1657131 [+], 1023526458444hypothetical protein  TssG
14BDL_4814 (clpV)1657118..1660165 [+], 3048526459217type VI secretion ATPase, ClpV1 family  TssH
15BDL_48151660192..1663215 [+], 3024526457471Rhs element Vgr family protein  TssI
16BDL_48161663241..1665883 [+], 2643526456780pentapeptide repeats family protein 
17BDL_48171665901..1666965 [+], 1065526457888pentapeptide repeats family protein 
18BDL_48181666962..1667714 [+], 753526457437hypothetical protein 
19BDL_48191667743..1668135 [+], 393526459099hypothetical protein 
20BDL_48201668145..1668942 [+], 798526458523type VI secretion lipofamily protein  TssJ
21BDL_48211668975..1670372 [+], 1398526458297hypothetical protein  TssK
22BDL_48221670369..1671034 [+], 666526456815type IV/VI secretion system , DotU family domain protein  TssL
23BDL_48231671046..1675104 [+], 4059526458070hypothetical protein  TssM
24BDL_48241675824..1677035 [+], 1212526457410ubiquitin carboxyl-terminal hydrolase family protein  BMAA0729 (e)
25BDL_48251677497..1678129 [+], 633526457009GTP cyclohydrolase I family protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
BMAA0742 , BMAA0729, BMAA0737

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BDL_48101653379..1653888 [+], 510526456830type VI secretion system effector, Hcp1 family protein BMAA0742
2BDL_48241675824..1677035 [+], 1212526457410ubiquitin carboxyl-terminal hydrolase family protein BMAA0729
3BDL_48151660192..1663215 [+], 3024526457471Rhs element Vgr family protein BMAA0737

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Proteins        Genes