SecReT6
I. Summary
SecReT6 ID834 insolico
StrainBurkholderia pseudomallei MSHR305
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_021884
Location2674996..2695016
Comment
FunctionN/A
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111011111
ComponentTssGTssJTssKTssM
Number1111
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BDL_22932670305..2671366 [+], 1062526471001macro domain protein 
2BDL_22942672209..2672535 [+], 327526473153baseplate J-like family protein 
3BDL_22952672528..2672941 [+], 414526472871phage tail protein I 
4BDL_22962672959..2673441 [+], 483526471622DNA methylase family protein 
5BDL_22972673964..2674425 [+], 462526471786putative transcription activator 
6BDL_22982674529..2674894 [-], 366526471780phage virion morphogenesis protein 
7BDL_22992674996..2675781 [-], 786526471466type IV/VI secretion system , DotU family domain protein  TssL
8BDL_23002675778..2677124 [-], 1347526472159hypothetical protein  TssK
9BDL_23012677233..2677847 [-], 615526473266type VI secretion lipofamily protein  TssJ
10BDL_23022678222..2678893 [+], 672526471121tetratricopeptide repeat family protein 
11BDL_23032678930..2679448 [+], 519526473160hypothetical protein  TssB
12BDL_23042679465..2680955 [+], 1491526470737hypothetical protein  TssC
13BDL_23052681028..2681531 [+], 504526470565type VI secretion system effector, Hcp1 family protein  TssD
14BDL_23062681589..2682071 [+], 483526470477lysozyme family protein  TssE
15BDL_23072682151..2683989 [+], 1839526472569hypothetical protein  TssF
16BDL_23082683953..2685053 [+], 1101526472033hypothetical protein  TssG
17BDL_2309 (clpV)2685087..2687756 [+], 2670526471044type VI secretion ATPase, ClpV1 family  TssH
18BDL_23102687846..2688967 [+], 1122526472464hypothetical protein  TssA
19BDL_23112689194..2690132 [-], 939526469934ompA family protein  TagL
20BDL_23122690137..2691126 [-], 990526470775hypothetical protein 
21BDL_23132691123..2695016 [-], 3894526471191intracellular multiplication and macrophage-killing family protein  TssM
22BDL_23142695295..2695822 [-], 528526470896D-alanyl-D-alanine carboxypeptidase family protein 
23BDL_23152696272..2697240 [+], 969526472679hypothetical protein 
24BDL_23162697450..2698898 [-], 1449526472145outer membrane efflux family protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BTH_II0090 , BTH_I3225, BTH_I3226, BTH_II0310, BTH_I3225, YPK_3563, BTH_I2693, BCAL0343, BTH_I0068, BTH_I2705, BTH_I2691, BTH_I2697

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BDL_44971247469..1249709 [-], 2241526457406hypothetical protein BTH_II0090
2BDL_44981249723..1252509 [-], 2787526457861Rhs element Vgr family protein BTH_I3225
3BDL_59133001035..3003275 [+], 2241526457937hypothetical protein BTH_I3226
4BDL_54452438213..2439118 [+], 906526458084D-mannose binding lectin family protein BTH_II0310
5BDL_59122998229..3001021 [+], 2793526459071Rhs element Vgr family protein BTH_I3225
6BDL_3745269738..270265 [+], 528526459131hypothetical protein YPK_3563
7BDL_579720506..723340 [-], 2835526470008Rhs element Vgr family protein BTH_I2693
8BDL_23052681028..2681531 [+], 504526470565type VI secretion system effector, Hcp1 family protein BCAL0343
9BDL_18772227029..2227469 [-], 441526470659hypothetical protein BTH_I0068
10BDL_588734167..736974 [-], 2808526472128Rhs element Vgr family protein BTH_I2705
11BDL_577716460..719483 [-], 3024526472353hypothetical protein BTH_I2691
12BDL_583725476..728811 [-], 3336526472738Rhs element Vgr family protein BTH_I2697

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Proteins        Genes

Homology Immunity protein list
BTH_I2700, BTH_I0069

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BDL_586732637..733194 [-], 558526471048hypothetical protein BTH_I2700
2BDL_18762226674..2227042 [-], 369526471453putative lipoprotein BTH_I0069

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Proteins        Genes
N/A

Genomics & Bioinformatics Group in MML, SJTU