I. Summary
SecReT6 ID835 insolico
StrainSalmonella enterica subsp. enterica serovar Newport str. USMARC-S3124.1
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SN31241_125101288519..1289739 [-], 1221528817965Membrane-bound lytic murein transglycosylase D 
2SN31241_125201289958..1290713 [-], 756528817966Hydroxyacylglutathione hydrolase 
3SN31241_125301290802..1291470 [+], 669528817967protein yafS 
4SN31241_125401291467..1291934 [-], 468528817968Ribonuclease H 
5SN31241_125501291989..1292729 [+], 741528817969DNA polymerase III subunit epsilon 
6SN31241_125601293261..1294316 [-], 1056528817970ImpA N  TssA
7SN31241_125701294327..1295322 [-], 996528817971Type VI secretion protein  TssG
8SN31241_125801295319..1297202 [-], 1884528817972Type VI secretion protein  TssF
9SN31241_125901297218..1297712 [-], 495528817973Type VI secretion system lysozyme-like protein  TssE
10SN31241_126001297709..1298533 [-], 825528817974SciE protein  TagJ
11SN31241_126101298520..1299410 [-], 891528817975cytoplasmic protein 
12SN31241_126201299790..1302429 [+], 2640528817976Chaperone protein ClpB  TssH
13SN31241_126301302529..1303071 [+], 543528817977Type VI secretion protein  TssB
14SN31241_126401303095..1304603 [+], 1509528817978Type VI secretion protein, EvpB  TssC
15SN31241_126501305029..1305454 [+], 426528817979hypothetical protein  STY0301 (i)
16SN31241_126601305691..1306176 [+], 486528817980Hemolysin-coregulated protein  TssD
17SN31241_126701306524..1306964 [+], 441528817981cytoplasmic protein  STM0277 (e)
18SN31241_126801307000..1307332 [+], 333528817982periplasmic protein  STM0278 (i)
19SN31241_126901307475..1307960 [+], 486528817983Hemolysin-coregulated protein  TssD
20SN31241_127001308072..1308563 [+], 492528817984Type VI secretion lipoprotein  TssJ
21SN31241_127101308567..1309910 [+], 1344528817985Type VI secretion protein  TssK
22SN31241_127201309907..1311211 [+], 1305528817986SciP protein  TssL
23SN31241_127301311216..1311989 [+], 774528817987inner membrane protein 
24SN31241_127401312266..1312622 [+], 357528817988SciR protein 
25SN31241_127501312656..1316525 [+], 3870528817989Type VI secretion protein IcmF  TssM
26SN31241_127601316540..1317292 [+], 753528817990cytoplasmic protein 
27SN31241_127701317850..1318251 [+], 402528817991hypothetical protein 
28SN31241_127801318260..1318382 [+], 123528817992cytoplasmic protein 
29SN31241_127901318379..1318795 [+], 417528817993secreted protein 
30SN31241_128001319218..1319340 [+], 123528817994cytoplasmic protein 
31SN31241_128101319482..1319691 [+], 210528817995hypothetical protein 
32SN31241_128201319737..1321926 [+], 2190528817996Rhs element Vgr  TssI
33SN31241_128301321950..1322396 [+], 447528817997hypothetical protein 
34SN31241_128401322415..1326494 [+], 4080528817998hypothetical protein  PAAR
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
EvpC , STM0277, EvpC, STY2606, ROD_34191

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SN31241_126601305691..1306176 [+], 486528817980Hemolysin-coregulated protein EvpC
2SN31241_126701306524..1306964 [+], 441528817981cytoplasmic protein STM0277
3SN31241_126901307475..1307960 [+], 486528817983Hemolysin-coregulated protein EvpC
4SN31241_348303511450..3511851 [+], 402528820196hypothetical protein STY2606
5SN31241_425704305918..4306403 [-], 486528820969hypothetical protein ROD_34191

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Proteins        Genes

Homology Immunity protein list
STY0301, STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SN31241_126501305029..1305454 [+], 426528817979hypothetical protein STY0301
2SN31241_126801307000..1307332 [+], 333528817982periplasmic protein STM0278
3SN31241_348403511851..3512369 [+], 519528820197lipoprotein STY2607

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Proteins        Genes