I. Summary
SecReT6 ID847 insolico
StrainVibrio campbellii ATCC BAA-1116
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1M892_223551006349..1007977 [-], 1629541870623T6SS/sigma-54-dependent transcriptional regulator VasH 
2M892_223601007964..1010648 [-], 2685541870624T6SS/ATPase, ClpA/B (ClpV1 family) VasG  TssH
3M892_223651011098..1011616 [+], 519541870625T6SS/hemolysin co-regulated protein Hcp  TssD
4M892_223701011689..1013767 [+], 2079541870626T6SS/ secreted protein VgrG  TssI
5M892_223751013767..1014252 [+], 486541870627hypothetical protein 
6M892_223801014354..1015673 [+], 1320541870628hypothetical protein 
7M892_223851015654..1016646 [+], 993541870629hypothetical protein 
8M892_223901016639..1017583 [+], 945541870630hypothetical protein 
9M892_223951017819..1019822 [+], 2004541871695T6SS/serine-threonine protein kinase TagE 
10M892_224001019822..1021423 [+], 1602541870631T6SS/ImpA domain protein VasJ  TssA
11M892_224051021450..1021956 [+], 507541870632T6SS/protein (ImpB family) VasQ  TssB
12M892_224101021965..1023440 [+], 1476541870633T6SS/protein (ImpC/EvpB family, DUF877) VasR  TssC
13M892_224151023502..1023912 [+], 411541871696T6SS/lysozyme-related protein (DUF1316) VasS  TssE
14M892_224201023923..1025671 [+], 1749541870634T6SS/protein (ImpG, DUF879) VasA  TssF
15M892_224251025668..1026666 [+], 999541870635T6SS/protein (ImpH, DUF1305) VasB  TssG
16M892_224301026766..1027218 [-], 453541871697T6SS/putative HTH-type transcriptional regulator Lrp/AsnC family 
17M892_224351027251..1030640 [-], 3390541870636T6SS/membrane protein (IcmF-like) VasK  TssM
18M892_224401030668..1031972 [-], 1305541870637T6SS/ImpA domain protein VasL  TssA
19M892_224451032595..1033194 [+], 600541871698T6SS/hypothetical protein (DUF820) 
20M892_224501033204..1034718 [+], 1515541870638T6SS/FHA-containing domain protein (ImpI family) VasC  Fha
21M892_224551034762..1035211 [+], 450541871699T6SS/lipoprotein VasD  TssJ
22M892_224601035223..1036548 [+], 1326541870639T6SS/protein (ImpJ family, DUF876) VasE  TssK
23M892_224651036545..1037336 [+], 792541870640T6SS/T4SS outer membrane protein (ImpK, DotU family) VasF  TssL
24M892_224701037440..1038360 [-], 921541871700transposase IS903 
25M892_224751038411..1038848 [-], 438541871701DNA-binding protein 
26M892_224801038941..1039426 [+], 486541871702hypothetical protein 
27M892_224851039677..1041833 [+], 2157541871703TonB-denpendent receptor 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
VPA1263 , VEPGS_0021, VP1388

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1M892_100902199433..2202012 [+], 2580541869767S-type Pyocin family VPA1263
2M892_223651011098..1011616 [+], 519541870625T6SS/hemolysin co-regulated protein Hcp VEPGS_0021
3M892_22335998499..1000097 [+], 1599541871691hypothetical protein VP1388

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Proteins        Genes

Homology Immunity protein list

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1M892_18605166712..167365 [+], 654541871355hypothetical protein v12G01_02260

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Proteins        Genes