I. Summary
SecReT6 ID851 insolico
StrainEscherichia coli LY180
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1LY180_142803001953..3003158 [+], 1206544391325cysteine sulfinate desulfinase 
2LY180_142853003158..3003601 [+], 444544391326CsdA-binding activator 
3LY180_142903003652..3004458 [-], 807544391327sulfur acceptor protein CsdL 
4LY180_14295 (mltA)3004535..3005632 [-], 1098544391328murein transglycosylase A 
5LY180_143153006772..3007272 [+], 501544391329hypothetical protein  TssB
6LY180_143203007331..3008869 [+], 1539544393080EvpB/family type VI secretion protein  TssC
7LY180_143253008887..3010224 [+], 1338544393081hypothetical protein  TssK
8LY180_143303010221..3010886 [+], 666544393082type VI secretion protein ImpK  TssL
9LY180_143353010899..3012551 [+], 1653544393083OmpA family protein  TagL
10LY180_143403012609..3013100 [+], 492544393084Hcp family type VI secretion system effector  TssD
11LY180_143453013291..3015936 [+], 2646544391330protein disaggregation chaperone  TssH
12LY180_143503015948..3018434 [+], 2487544393085type IV secretion protein Rhs  TssI
13LY180_143553018436..3019287 [+], 852544393086hypothetical protein 
14LY180_143603019277..3019813 [+], 537544393087hypothetical protein 
15LY180_143653020138..3022645 [+], 2508544393088type IV secretion protein Rhs  TssI
16LY180_143703022846..3023268 [+], 423544393089hypothetical protein 
17LY180_143753023270..3023821 [+], 552544393090hypothetical protein 
18LY180_143803023899..3025113 [+], 1215544393091hypothetical protein 
19LY180_143853025113..3028502 [+], 3390544393092type VI secretion protein VasK  TssM
20LY180_143903028495..3030105 [+], 1611544393093hypothetical protein  TssA
21LY180_143953030105..3031028 [+], 924544393094Paar  PAAR
22LY180_144003031025..3031423 [+], 399544393095hypothetical protein 
23LY180_144053031478..3031585 [+], 108544393096hypothetical protein 
24LY180_144103031736..3032029 [+], 294544393097hypothetical protein 
25LY180_144153032130..3033488 [+], 1359544393098hypothetical protein  TssA
26LY180_144203033963..3034640 [-], 678544391331transposase 
27LY180_144253034829..3035140 [-], 312544393099transposase IS3 
28LY180_144303036166..3036588 [+], 423544393100hypothetical protein 
29LY180_144353037148..3038908 [+], 1761544393101type VI secretion protein ImpG  TssF
30LY180_144403038872..3039951 [+], 1080544393102hypothetical protein  TssG
31LY180_144453039932..3040468 [+], 537544393103type VI secretion protein  TssJ
32LY180_144503040496..3040900 [+], 405544393104hypothetical protein  TssE
33LY180_144553040900..3042276 [+], 1377544393105impA family protein  TssA
34LY180_144603042341..3042889 [+], 549544393106transcriptional regulator 
35LY180_14465 (amiC)3043235..3044488 [-], 1254544391332N-acetylmuramoyl-L-alanine amidase 
36LY180_144703044720..3046051 [+], 1332544391333N-acetylglutamate synthase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1LY180_143403012609..3013100 [+], 492544393084Hcp family type VI secretion system effector EC042_4529

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