I. Summary

SecReT6 ID	862
Strain	Escherichia coli JJ1886
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_022648
Location	3133230..3176783
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	3	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	2	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	P423_15360	3128410..3129615 [+], 1206	556552721	cysteine sulfinate desulfinase
2	P423_15365	3129615..3130058 [+], 444	556552722	CsdA-binding activator
3	P423_15370	3130109..3130915 [-], 807	556552723	sulfur acceptor protein CsdL
4	P423_15375 (mltA)	3130992..3132089 [-], 1098	556552724	murein transglycosylase A
5	P423_15395	3133230..3133730 [+], 501	556552725	hypothetical protein	TssB
6	P423_15400	3133789..3135327 [+], 1539	556554732	EvpB/family type VI secretion protein	TssC
7	P423_15405	3135345..3136682 [+], 1338	556554733	hypothetical protein	TssK
8	P423_15410	3136679..3137344 [+], 666	556554734	type VI secretion protein ImpK	TssL
9	P423_15415	3137357..3139009 [+], 1653	556554735	OmpA family protein	TagL
10	P423_15420	3139067..3139558 [+], 492	556554736	Hcp family type VI secretion system effector	TssD
11	P423_15425	3139749..3142385 [+], 2637	556552726	protein disaggregation chaperone	TssH
12	P423_15430	3142397..3144721 [+], 2325	556554737	type IV secretion protein Rhs	TssI
13	P423_15435	3144733..3147096 [+], 2364	556554738	hypothetical protein
14	P423_15440	3147093..3147950 [+], 858	556554739	hypothetical protein
15	P423_15445	3148414..3150792 [+], 2379	556554740	type IV secretion protein Rhs	TssI
16	P423_15450	3150795..3151616 [+], 822	556554741	hypothetical protein
17	P423_15455	3151660..3152187 [+], 528	556554742	hypothetical protein
18	P423_15460	3152184..3154052 [+], 1869	556554743	hypothetical protein
19	P423_15465	3154158..3156671 [+], 2514	556554744	type IV secretion protein Rhs	TssI
20	P423_15470	3156693..3157295 [+], 603	556554745	hypothetical protein
21	P423_15475	3157398..3157847 [+], 450	556554746	hypothetical protein
22	P423_15480	3157925..3159139 [+], 1215	556554747	hypothetical protein
23	P423_15485	3159139..3160818 [+], 1680	556554748	hypothetical protein
24	P423_15490	3161184..3162500 [+], 1317	556554749	hypothetical protein
25	P423_15495	3162515..3163261 [+], 747	556554750	ATP-binding protein
26	P423_15500	3163312..3165114 [+], 1803	556554751	membrane protein	TssM
27	P423_15505	3165107..3166717 [+], 1611	556554752	hypothetical protein	TssA
28	P423_15510	3166717..3168141 [+], 1425	556554753	paar	PAAR
29	P423_15515	3168134..3168556 [+], 423	556554754	hypothetical protein
30	P423_15520	3169116..3170876 [+], 1761	556554755	type VI secretion protein ImpG	TssF
31	P423_15525	3170840..3171919 [+], 1080	556554756	hypothetical protein	TssG
32	P423_15530	3171900..3172244 [+], 345	556554757	hypothetical protein	TssJ
33	P423_15535	3173891..3174241 [-], 351	556552727	isocitrate lyase
34	P423_15540	3174238..3174663 [-], 426	556554758	transposase
35	P423_15545	3174799..3174975 [+], 177	556554759	hypothetical protein	TssJ
36	P423_15550	3174979..3175407 [+], 429	556554760	hypothetical protein	TssE
37	P423_15555	3175407..3176783 [+], 1377	556554761	impA family protein	TssA
38	P423_15560	3177083..3178030 [-], 948	556554762	phosphoglycerate dehydrogenase
39	P423_15565	3178102..3178698 [-], 597	556554763	isomerase
40	P423_15570	3178701..3179876 [-], 1176	556554764	aminotransferase
41	P423_15575	3179876..3181456 [-], 1581	556552728	PTS maltose transporter subunit IICB

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	P423_15420	3139067..3139558 [+], 492	556554736	Hcp family type VI secretion system effector	EC042_4529

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Proteins        Genes

N/A

N/A