SecReT6
I. Summary
SecReT6 ID863 insolico
StrainBurkholderia pseudomallei NCTC 13179
Repliconchromosome II [Browse all T6SS(s) in this replicon]
AccessionNC_022658
Location801727..821622
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1010
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BBK_4107797072..798898 [-], 1827556573565impA-related N-terminal family protein  TssA
2BBK_4108798889..799626 [-], 738556571937transcriptional regulatory , C terminal family protein  VirG
3BBK_4109799623..801467 [-], 1845556573090histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein  VirA
4BBK_4110801727..802221 [+], 495556573842hypothetical protein  TssB
5BBK_4111802218..803744 [+], 1527556572484hypothetical protein  TssC
6BBK_4112803964..804473 [+], 510556574306type VI secretion system effector, Hcp1 family protein  TssD
7BBK_4113804466..804927 [+], 462556574225lysozyme family protein  TssE
8BBK_4114804964..806706 [+], 1743556572936hypothetical protein  TssF
9BBK_4115806694..807716 [+], 1023556573262hypothetical protein  TssG
10BBK_4116 (clpV)807703..810750 [+], 3048556572794type VI secretion ATPase, ClpV1 family  TssH
11BBK_4117810777..813800 [+], 3024556573804Rhs element Vgr family protein  TssI
12BBK_4118813826..816468 [+], 2643556572335pentapeptide repeats family protein 
13BBK_4119816486..817550 [+], 1065556573194pentapeptide repeats family protein 
14BBK_4120817664..818302 [+], 639556571979hypothetical protein 
15BBK_4121818331..818723 [+], 393556572183hypothetical protein 
16BBK_4122818733..819530 [+], 798556572430type VI secretion lipofamily protein 
17BBK_4123819563..820960 [+], 1398556572640hypothetical protein  TssK
18BBK_4124820957..821622 [+], 666556572580type IV/VI secretion system , DotU family domain protein  TssL
19BBK_4125 (icmF1)821753..823642 [+], 1890556571957icmF1 domain protein 
20BBK_4126823846..825675 [+], 1830556572706hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BMAA0737 , YPK_3563, BMAA0742

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BBK_4117810777..813800 [+], 3024556573804Rhs element Vgr family protein BMAA0737
2BBK_57232743994..2744521 [+], 528556574278hypothetical protein YPK_3563
3BBK_4112803964..804473 [+], 510556574306type VI secretion system effector, Hcp1 family protein BMAA0742

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Proteins        Genes
N/A
N/A