I. Summary

SecReT6 ID	864
Strain	Burkholderia pseudomallei NCTC 13179
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_022658
Location	1672290..1695519
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	0	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BBK_4850	1667319..1667576 [+], 258	556572574	putative tn501 transposition transposase
2	BBK_4851	1668308..1669093 [+], 786	556573261	hypothetical protein
3	BBK_4852	1669142..1669426 [+], 285	556574037	hypothetical protein
4	BBK_4853	1669714..1669827 [-], 114	556572459	hypothetical protein
5	BBK_4854	1669824..1670423 [-], 600	556573494	hypothetical protein
6	BBK_4855	1670621..1671076 [-], 456	556572374	hemolysin secretion/activation ShlB/FhaC/HecB family protein
7	BBK_4856	1671258..1672112 [-], 855	556573278	hypothetical protein
8	BBK_4857	1672146..1672274 [-], 129	556573503	hypothetical protein
9	BBK_4858	1672290..1674494 [-], 2205	556572343	Rhs element Vgr family protein	TssI
10	BBK_4859 (clpV)	1674491..1677157 [-], 2667	556572187	type VI secretion ATPase, ClpV1 family	TssH
11	BBK_4860	1677136..1678590 [-], 1455	556573343	hypothetical protein	TssG
12	BBK_4861	1678587..1680458 [-], 1872	556572834	hypothetical protein	TssF
13	BBK_4862	1680463..1681035 [-], 573	556574140	lysozyme family protein	TssE
14	BBK_4863 (hcp1)	1681054..1681545 [-], 492	556571900	protein hcp1	TssD
15	BBK_4864	1681605..1683113 [-], 1509	556573055	hypothetical protein	TssC
16	BBK_4865	1683106..1683684 [-], 579	556574372	hypothetical protein	TssB
17	BBK_4866	1683747..1684826 [-], 1080	556574253	impA-related N-terminal family protein
18	BBK_4867	1684879..1685097 [-], 219	556571908	serine/threonine kinase domain protein
19	BBK_4868	1685040..1687499 [-], 2460	556572029	kinase domain protein
20	BBK_4869	1687708..1688640 [-], 933	556572134	hypothetical protein
21	BBK_4870	1688637..1692266 [-], 3630	556573159	intracellular multiplication and macrophage-killing family protein	TssM
22	BBK_4871	1692269..1693585 [-], 1317	556572182	type VI secretion system OmpA/MotB family protein	TssL
23	BBK_4872	1693601..1695004 [-], 1404	556572666	hypothetical protein	TssK
24	BBK_4873	1695001..1695519 [-], 519	556574273	type VI secretion lipofamily protein	TssJ
25	BBK_4874	1696201..1696560 [+], 360	556572390	hypothetical protein
26	BBK_4875	1696615..1698051 [+], 1437	556573574	FHA domain protein	Fha
27	BBK_4876	1698094..1699974 [-], 1881	556572637	transglutaminase-like superfamily protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

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