I. Summary
SecReT6 ID868 insolico
StrainBurkholderia pseudomallei NCTC 13179
Repliconchromosome I [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BBK_17912071604..2071930 [+], 327556575616baseplate J-like family protein 
2BBK_17922072032..2072334 [+], 303556577691phage tail protein I 
3BBK_17932072480..2072836 [+], 357556575286DNA methylase family protein 
4BBK_17942073099..2073821 [+], 723556575056TENA/THI-4/PQQC family protein 
5BBK_17952073925..2074290 [-], 366556576284phage virion morphogenesis protein 
6BBK_17962074392..2075177 [-], 786556575484type IV/VI secretion system , DotU family domain protein  TssL
7BBK_17972075174..2076520 [-], 1347556575570hypothetical protein  TssK
8BBK_17982076629..2077243 [-], 615556575684type VI secretion lipofamily protein  TssJ
9BBK_17992077618..2078289 [+], 672556576509tetratricopeptide repeat family protein 
10BBK_18002078326..2078844 [+], 519556577547hypothetical protein  TssB
11BBK_18012078860..2080350 [+], 1491556574594hypothetical protein  TssC
12BBK_18022080423..2080926 [+], 504556577663type VI secretion system effector, Hcp1 family protein  TssD
13BBK_18032080984..2081466 [+], 483556576979lysozyme family protein  TssE
14BBK_18042081546..2083384 [+], 1839556574763hypothetical protein  TssF
15BBK_18052083348..2084448 [+], 1101556575241hypothetical protein  TssG
16BBK_1806 (clpV)2084482..2087151 [+], 2670556575436type VI secretion ATPase, ClpV1 family  TssH
17BBK_18072087239..2088360 [+], 1122556576504impA-related N-terminal family protein  TssA
18BBK_18082088559..2089491 [-], 933556577381ompA family protein  TagL
19BBK_18092089496..2090485 [-], 990556575468hypothetical protein 
20BBK_18102090482..2094375 [-], 3894556576822intracellular multiplication and macrophage-killing family protein  TssM
21BBK_18112094647..2095174 [-], 528556576616D-alanyl-D-alanine carboxypeptidase family protein 
22BBK_18122095624..2096586 [+], 963556576875hypothetical protein 
23BBK_18132096796..2098244 [-], 1449556577352outer membrane efflux family protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
BTH_I3226 , BTH_I3225, BTH_I3225, BTH_I3226, BTH_II0310, BTH_I2705, BTH_I2693, BTH_I2698, BTH_I0068, BTH_I2697, BCAL0343

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BBK_52122100942..2103182 [+], 2241556571821hypothetical protein BTH_I3226
2BBK_58982978740..2980968 [+], 2229556573414phage late control D family protein BTH_I3225
3BBK_52112098142..2100928 [+], 2787556573600Rhs element Vgr family protein BTH_I3225
4BBK_58992980982..2983222 [+], 2241556573854hypothetical protein BTH_I3226
5BBK_47731571085..1571990 [+], 906556573940D-mannose binding lectin family protein BTH_II0310
6BBK_95126312..129119 [-], 2808556574852Rhs element Vgr family protein BTH_I2705
7BBK_87113366..116206 [-], 2841556576181Rhs element Vgr family protein BTH_I2693
8BBK_92121787..123109 [-], 1323556576624hypothetical protein BTH_I2698
9BBK_13641600896..1601336 [-], 441556576714hypothetical protein BTH_I0068
10BBK_91118343..121678 [-], 3336556577169Rhs element Vgr family protein BTH_I2697
11BBK_18022080423..2080926 [+], 504556577663type VI secretion system effector, Hcp1 family protein BCAL0343

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Proteins        Genes

Homology Immunity protein list
BTH_I2700, BTH_I0069

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BBK_93124782..125339 [-], 558556574985hypothetical protein BTH_I2700
2BBK_13621600541..1600909 [-], 369556577793putative lipoprotein BTH_I0069

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Proteins        Genes