I. Summary
SecReT6 ID871 insolico
StrainPseudomonas aeruginosa PA1R
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PA1R_gp35884015742..4018840 [-], 3099558669492Serine/threonine protein kinase  PpkA
2PA1R_gp35894018848..4019576 [-], 729558669493Phosphoprotein phosphatase PppA  PppA
3PA1R_gp35904019586..4020266 [-], 681558669494Protein phosphatase ImpM  TagF
4PA1R_gp35914020263..4023796 [-], 3534558669495IcmF-related protein  TssM
5PA1R_gp35924023793..4025142 [-], 1350558669496Outer membrane protein ImpK/VasF, OmpA/MotB domain protein  TssL
6PA1R_gp35934025149..4026483 [-], 1335558669497Uncharacterized protein ImpJ/VasE  TssK
7PA1R_gp35944026499..4026963 [-], 465558669498Type VI secretion lipoprotein/VasD  TssJ
8PA1R_gp35954027008..4028501 [-], 1494558669499Uncharacterized protein ImpI/VasC  Fha
9PA1R_gp35964028869..4029903 [+], 1035558669500Uncharacterized protein ImpA  TssA
10PA1R_gp35974029992..4030510 [+], 519558669501Uncharacterized protein ImpB  TssB
11PA1R_gp35984030523..4032019 [+], 1497558669502Uncharacterized protein ImpC  TssC
12PA1R_gp35994032095..4032583 [+], 489558669503Uncharacterized protein ImpD  TssD
13PA1R_gp36004032811..4033596 [+], 786558669504Protein of avirulence locus ImpE  TagJ
14PA1R_gp36014033598..4034107 [+], 510558669505Uncharacterized protein ImpF  TssE
15PA1R_gp36024034104..4035963 [+], 1860558669506Protein ImpG/VasA  TssF
16PA1R_gp36034035927..4036973 [+], 1047558669507Uncharacterized protein ImpH/VasB  TssG
17PA1R_gp36044036966..4039674 [+], 2709558669508ClpB protein  TssH
18PA1R_gp36054039712..4041652 [+], 1941558669509VgrG protein  TssI
19PA1R_gp36064041767..4042051 [-], 285558669510hypothetical protein  Tsi6 (i)
20PA1R_gp36074042048..4043340 [-], 1293558669511Rhs family protein  Tse6 (e)
21PA1R_gp36084043356..4043790 [-], 435558669512hypothetical protein 
22PA1R_gp36094044044..4046269 [+], 2226558669513VgrG protein  TssI
23PA1R_gp36104046297..4046746 [+], 450558669514hypothetical protein 
24PA1R_gp36114046763..4047875 [+], 1113558669515hypothetical protein 
25PA1R_gp36124047872..4048909 [+], 10385586695163-oxoacyl-[ACP] synthase 
26PA1R_gp36134048910..4049857 [+], 948558669517hypothetical protein 
27PA1R_gp36144049868..4050782 [+], 915558669518hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
PA2684 , PA2685, PA0093, PA0091, PA2702, PA2774, PA3484, PA0085, PA0091, PA0093, PA0095, PA1844

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PA1R_gp0488602419..606372 [-], 3954558666446Rhs family protein PA2684
2PA1R_gp0489606422..608491 [-], 2070558666447VgrG protein PA2685
3PA1R_gp0491609195..610487 [+], 1293558666449Rhs family protein PA0093
4PA1R_gp0493610883..612823 [-], 1941558666451VgrG protein PA0091
5PA1R_gp0510631838..632314 [+], 477558666468hypothetical protein PA2702
6PA1R_gp0595715106..715693 [-], 588558666552hypothetical protein PA2774
7PA1R_gp13251489399..1490625 [+], 1227558667263hypothetical protein PA3484
8PA1R_gp35994032095..4032583 [+], 489558669503Uncharacterized protein ImpD PA0085
9PA1R_gp36054039712..4041652 [+], 1941558669509VgrG protein PA0091
10PA1R_gp36074042048..4043340 [-], 1293558669511Rhs family protein PA0093
11PA1R_gp36094044044..4046269 [+], 2226558669513VgrG protein PA0095
12PA1R_gp54706069226..6069690 [-], 465558671355hypothetical protein PA1844

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Proteins        Genes

Homology Immunity protein list
PA0092, PA2703, PA2775, PA3485, PA0092, PA1845

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PA1R_gp0492610484..610768 [+], 285558666450hypothetical protein PA0092
2PA1R_gp0511632324..632557 [+], 234558666469hypothetical protein PA2703
3PA1R_gp0596715698..716135 [-], 438558666553hypothetical protein PA2775
4PA1R_gp13261490622..1491059 [+], 438558667264hypothetical protein PA3485
5PA1R_gp36064041767..4042051 [-], 285558669510hypothetical protein PA0092
6PA1R_gp54716069732..6070250 [-], 519558671356hypothetical protein PA1845

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Proteins        Genes