I. Summary
SecReT6 ID874 insolico
StrainPseudomonas aeruginosa PA1
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PA1S_gp35884015742..4018840 [-], 3099558675843Serine/threonine protein kinase  PpkA
2PA1S_gp35894018848..4019576 [-], 729558675844Phosphoprotein phosphatase PppA  PppA
3PA1S_gp35904019586..4020266 [-], 681558675845Protein phosphatase ImpM  TagF
4PA1S_gp35914020263..4023796 [-], 3534558675846IcmF-related protein  TssM
5PA1S_gp35924023793..4025142 [-], 1350558675847Outer membrane protein ImpK/VasF, OmpA/MotB domain protein  TssL
6PA1S_gp35934025149..4026483 [-], 1335558675848Uncharacterized protein ImpJ/VasE  TssK
7PA1S_gp35944026499..4026963 [-], 465558675849Type VI secretion lipoprotein/VasD  TssJ
8PA1S_gp35954027008..4028501 [-], 1494558675850Uncharacterized protein ImpI/VasC  Fha
9PA1S_gp35964028869..4029903 [+], 1035558675851Uncharacterized protein ImpA  TssA
10PA1S_gp35974029992..4030510 [+], 519558675852Uncharacterized protein ImpB  TssB
11PA1S_gp35984030523..4032019 [+], 1497558675853Uncharacterized protein ImpC  TssC
12PA1S_gp35994032095..4032583 [+], 489558675854Uncharacterized protein ImpD  TssD
13PA1S_gp36004032811..4033596 [+], 786558675855Protein of avirulence locus ImpE  TagJ
14PA1S_gp36014033598..4034107 [+], 510558675856Uncharacterized protein ImpF  TssE
15PA1S_gp36024034104..4035963 [+], 1860558675857Protein ImpG/VasA  TssF
16PA1S_gp36034035927..4036973 [+], 1047558675858Uncharacterized protein ImpH/VasB  TssG
17PA1S_gp36044036966..4039674 [+], 2709558675859ClpB protein  TssH
18PA1S_gp36054039712..4041652 [+], 1941558675860VgrG protein  TssI
19PA1S_gp36064041767..4042051 [-], 285558675861hypothetical protein  Tsi6 (i)
20PA1S_gp36074042048..4043340 [-], 1293558675862Rhs family protein  Tse6 (e)
21PA1S_gp36084043356..4043790 [-], 435558675863hypothetical protein 
22PA1S_gp36094044044..4046269 [+], 2226558675864VgrG protein  TssI
23PA1S_gp36104046297..4046746 [+], 450558675865hypothetical protein 
24PA1S_gp36114046763..4047875 [+], 1113558675866hypothetical protein 
25PA1S_gp36124047872..4048909 [+], 10385586758673-oxoacyl-[ACP] synthase 
26PA1S_gp36134048910..4049857 [+], 948558675868hypothetical protein 
27PA1S_gp36144049868..4050782 [+], 915558675869hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
PA2684 , PA2685, PA0093, PA0091, PA2702, PA2774, PA3484, PA0085, PA0091, PA0093, PA0095, PA1844

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PA1S_gp0488602419..606372 [-], 3954558672797Rhs family protein PA2684
2PA1S_gp0489606422..608491 [-], 2070558672798VgrG protein PA2685
3PA1S_gp0491609195..610487 [+], 1293558672800Rhs family protein PA0093
4PA1S_gp0493610883..612823 [-], 1941558672802VgrG protein PA0091
5PA1S_gp0510631838..632314 [+], 477558672819hypothetical protein PA2702
6PA1S_gp0595715106..715555 [-], 450558672903hypothetical protein PA2774
7PA1S_gp13251489399..1490625 [+], 1227558673614hypothetical protein PA3484
8PA1S_gp35994032095..4032583 [+], 489558675854Uncharacterized protein ImpD PA0085
9PA1S_gp36054039712..4041652 [+], 1941558675860VgrG protein PA0091
10PA1S_gp36074042048..4043340 [-], 1293558675862Rhs family protein PA0093
11PA1S_gp36094044044..4046269 [+], 2226558675864VgrG protein PA0095
12PA1S_gp54706069226..6069690 [-], 465558677706hypothetical protein PA1844

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Proteins        Genes

Homology Immunity protein list
PA0092, PA2703, PA2775, PA3485, PA0092, PA1845

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PA1S_gp0492610484..610768 [+], 285558672801hypothetical protein PA0092
2PA1S_gp0511632324..632557 [+], 234558672820hypothetical protein PA2703
3PA1S_gp0596715698..716135 [-], 438558672904hypothetical protein PA2775
4PA1S_gp13261490622..1491059 [+], 438558673615hypothetical protein PA3485
5PA1S_gp36064041767..4042051 [-], 285558675861hypothetical protein PA0092
6PA1S_gp54716069732..6070250 [-], 519558677707hypothetical protein PA1845

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Proteins        Genes