I. Summary
SecReT6 ID887 insolico
StrainPseudomonas aeruginosa LES431
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1T223_0038586086..89184 [-], 3099568151260serine/threonine protein kinase  PpkA
2T223_0039089192..89920 [-], 729568151261PppA  PppA
3T223_0039589930..90610 [-], 681568151262type VI secretion system protein ImpM  TagF
4T223_0040090607..94137 [-], 3531568151263type VI secretion protein IcmF  TssM
5T223_0040594134..95483 [-], 1350568151264type VI secretion protein  TssL
6T223_0041095490..96824 [-], 1335568151265type VI secretion protein  TssK
7T223_0041596840..97304 [-], 465568151266type VI secretion protein  TssJ
8T223_0042097349..98836 [-], 1488568151267signal peptide protein  Fha
9T223_0042599204..100238 [+], 1035568151268type VI secretion protein ImpA  TssA
10T223_00430100327..100845 [+], 519568151269hypothetical protein  TssB
11T223_00435100858..102354 [+], 1497568151270EvpB family type VI secretion protein  TssC
12T223_00440102430..102918 [+], 489568151271hypothetical protein  TssD
13T223_00445103146..103931 [+], 786568151272virulence protein, SciE type  TagJ
14T223_00450103933..104442 [+], 510568151273hypothetical protein  TssE
15T223_00455104439..106298 [+], 1860568151274type VI secretion system protein ImpG  TssF
16T223_00460106262..107308 [+], 1047568151275type VI secretion protein  TssG
17T223_00465107301..110009 [+], 2709568151276ATPase AAA  TssH
18T223_00470110047..111987 [+], 1941568151277type VI secretion protein ImpA  TssI
19T223_00475112102..112386 [-], 285568151278hypothetical protein  Tsi6 (i)
20T223_00490113691..114125 [-], 435568151279hypothetical protein 
21T223_00495114379..116604 [+], 2226568151280type VI secretion protein ImpA  TssI
22T223_00500116632..117081 [+], 450568151281hypothetical protein 
23T223_00505117098..118210 [+], 1113568151282hypothetical protein 
24T223_00510118207..119244 [+], 10385681512833-oxoacyl-ACP synthase 
25T223_00515119245..120192 [+], 948568151284hypothetical protein 
26T223_00520120203..121117 [+], 915568151285hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
PA0085 , PA0091, PA0095, PA3484, PA2774, PA2702, PA2685, PA2684, PA1844

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1T223_00440102430..102918 [+], 489568151271hypothetical protein PA0085
2T223_00470110047..111987 [+], 1941568151277type VI secretion protein ImpA PA0091
3T223_00495114379..116604 [+], 2226568151280type VI secretion protein ImpA PA0095
4T223_076101616602..1617828 [-], 1227568152669hypothetical protein PA3484
5T223_116402428633..2429220 [+], 588568153442hypothetical protein PA2774
6T223_122302537304..2537780 [-], 477568153549hypothetical protein PA2702
7T223_123152556812..2558881 [+], 2070568153566type VI secretion protein ImpA PA2685
8T223_123202558931..2562884 [+], 3954568153567hypothetical protein PA2684
9T223_177853810976..3811440 [+], 465568154627hypothetical protein PA1844

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Proteins        Genes

Homology Immunity protein list
PA0092, PA3485, PA2775, PA2703, Tsi5, PA1845

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1T223_00475112102..112386 [-], 285568151278hypothetical protein PA0092
2T223_076051616162..1616605 [-], 444568152668hypothetical protein PA3485
3T223_116352428191..2428628 [+], 438568153441hypothetical protein PA2775
4T223_122252537061..2537294 [-], 234568153548hypothetical protein PA2703
5T223_123252562881..2563072 [+], 192568153568hypothetical protein Tsi5
6T223_177803810416..3810934 [+], 519568154626hypothetical protein PA1845

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Proteins        Genes