I. Summary

SecReT6 ID	89
Strain	Ralstonia eutropha JMP134
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_007348
Location	2003017..2040567
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	Reut_B5248	1998268..1998471 [+], 204	73539071	hypothetical protein
2	Reut_B5249	1998568..1999140 [+], 573	73539072	transmembrane protein
3	Reut_B5250	1999144..2000082 [-], 939	73539073	LysR family transcriptional regulator
4	Reut_B5251	2000235..2001251 [+], 1017	73539074	hypothetical protein
5	Reut_B5252	2001297..2003006 [+], 1710	73539075	hypothetical protein
6	Reut_B5253	2003017..2003916 [-], 900	73539076	hypothetical protein
7	Reut_B5254	2004256..2005080 [-], 825	73539077	NAD-dependent deacetylase
8	Reut_B5255	2005077..2005436 [-], 360	73539078	hypothetical protein
9	Reut_B5256	2005379..2005708 [-], 330	73539079	hypothetical protein
10	Reut_B5257	2005753..2005989 [-], 237	73539080	hypothetical protein
11	Reut_B5258	2006216..2008549 [+], 2334	73539081	patatin
12	Reut_B5259	2008750..2009184 [-], 435	73539082	hypothetical protein	TssE
13	Reut_B5260	2009181..2011922 [-], 2742	73539083	ATPase AAA	TssH
14	Reut_B5261	2011957..2012442 [-], 486	73539084	hypothetical protein	TssD
15	Reut_B5262	2012449..2014176 [-], 1728	73539085	OmpA/MotB protein	TagL
16	Reut_B5263	2014181..2014828 [-], 648	73539086	hypothetical protein	TssL
17	Reut_B5264	2014825..2016171 [-], 1347	73539087	hypothetical protein	TssK
18	Reut_B5265	2016287..2017834 [-], 1548	73539088	hypothetical protein	TssC
19	Reut_B5266	2017859..2018365 [-], 507	73539089	hypothetical protein	TssB
20	Reut_B5267	2018664..2021132 [+], 2469	73539090	Rhs element Vgr protein	TssI
21	Reut_B5268	2021156..2022934 [+], 1779	73539091	hypothetical protein
22	Reut_B5269	2022931..2023839 [+], 909	73539092	signal peptide protein
23	Reut_B5270	2024056..2025384 [+], 1329	73539093	hypothetical protein
24	Reut_B5271	2025768..2029238 [+], 3471	73539094	hypothetical protein	TssM
25	Reut_B5272	2029244..2030818 [+], 1575	73539095	hypothetical protein	TssA
26	Reut_B5273	2030836..2032662 [+], 1827	73539096	hypothetical protein	TssF
27	Reut_B5274	2032659..2033708 [+], 1050	73539097	hypothetical protein	TssG
28	Reut_B5275	2033721..2034359 [+], 639	73539098	hypothetical protein	TssJ
29	Reut_B5276	2034417..2035232 [-], 816	73539099	regulatory protein IclR
30	Reut_B5277	2035363..2036346 [+], 984	73539100	hypothetical protein
31	Reut_B5278	2036393..2038744 [+], 2352	73539101	cytochrome P450:oxidoreductase FAD/NAD(P)-binding protein
32	Reut_B5279	2039056..2040567 [+], 1512	73539102	aldehyde dehydrogenase
33	Reut_B5280	2040820..2041776 [+], 957	73539103	LysR family transcriptional regulator
34	Reut_B5281	2041853..2042293 [-], 441	73539104	hypothetical protein
35	Reut_B5282	2042312..2043484 [-], 1173	73539105	hypothetical protein
36	Reut_B5283	2043481..2044272 [-], 792	73539106	enoyl-CoA hydratase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	Reut_B5261	2011957..2012442 [-], 486	73539084	hypothetical protein	EC042_4529

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation