SecReT6
SecReT6 ID896 experimental
StrainSalmonella enterica subsp. enterica serovar Typhimurium SR11
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionAJ320483
Location322..27706
CommentThe SCI island modulates serovar Typhimurium ability to enter eukaryotic cells
Functionanti-eukaryotic
T6SS TypeType i; subtype i3
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121111111
ComponentTssGTssJTssKTssM
Number1111
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1- (sciA)322..1377 [-], 105615130916SciA protein  TssA
2- (sciB)1388..2263 [-], 87615130917SciB protein  TssG
3- (sciC)2382..4265 [-], 188415130918SciC protein  TssF
4- (sciD)4281..4775 [-], 49515130919SciD protein  TssE
5- (sciE)4772..5611 [-], 84015130920SciE protein  TagJ
6- (sciF)5583..6485 [-], 90315130921SciF protein 
7- (sciG)6853..9492 [+], 264015130922SciG protein  TssH
8- (sciH)9592..10134 [+], 54315130923SciH protein  TssB
9- (sciI)10158..11651 [+], 149415130924SciI protein  TssC
10- (sciJ)11837..12283 [+], 44715130925SciJ protein 
11- (sciK)12537..13022 [+], 48615130926SciK protein  TssD
12- (sciL)13327..13812 [+], 48615130927SciL protein 
13- (sciM)14323..14808 [+], 48615130928SciM protein  TssD
14- (sciN)14920..15411 [+], 49215130929SciN protein  TssJ
15- (sciO)15415..16758 [+], 134415130930SciO protein  TssK
16- (sciP)16755..18059 [+], 130515130931SciP protein  TssL
17- (sciQ)18064..18837 [+], 77415130932SciQ protein 
18- (sciR)19028..19471 [+], 44415130933SciR protein 
19- (sciS)19505..23374 [+], 387015130934SciS protein  TssM
20- (sciT)23374..24162 [+], 78915130935SciT protein 
21- (sciU)24159..24575 [+], 41715130936SciU protein 
22- (sciV)24599..25120 [+], 52215130937SciV protein 
23- (vrgS)25517..27706 [+], 219015130938VrgS protein  TssI
24- (sciw)27730..28176 [+], 44715130939SciW protein 
25- (rhs1)28195..31791 [+], 359715130940Rhs1 protein  PAAR
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 






Homology effector (effector protein label, when available)
Homology immunity protein (immunity protein label, when available)
(1) Folkesson A et al. (2002). The Salmonella enterica subspecies I specific centisome 7 genomic island encodes novel protein families present in bacteria living in close contact with eukaryotic cells. Res Microbiol. 153(8):537-45. [PudMed:12437215] experimental
 
experimental This literature contains experimental investigation