SecReT6
I. Summary
SecReT6 ID907 experimental
StrainBacteroides fragilis NCTC 9343
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_003228
Location2346972..2370693
CommentBacteroides fragilis targets B. thetaiotaomicron via T6SS; deletion of tssC in B. fragilis renders this species largely unable to reduce B. thetaiotaomicron growth.
Functionanti-bacterial
T6SS TypeType iii
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
ComponentVgrGClpVTssBTssCTssETssFTssGTssKTssN
Number111111111
ComponentTssOTssPHcp
Number215
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BF20012344189..2344557 [-], 36960681489hypothetical protein 
2BF20022344598..2346970 [-], 237360681490hypothetical protein 
3BF20032346972..2347865 [-], 89460681491hypothetical protein  TssP
4BF20042347862..2348389 [-], 52860681492hypothetical protein  TssO
5BF20052348402..2348905 [-], 50460681493hypothetical protein  TssO
6BF20062348911..2349867 [-], 95760681494hypothetical protein  TssG
7BF20072349869..2351011 [-], 114360681495hypothetical protein  TssK
8BF20082351039..2351887 [-], 84960681496hypothetical protein  TssN
9BF20092352024..2352944 [-], 92160681497hypothetical protein 
10BF20102352949..2353995 [-], 104760681498hypothetical protein 
11BF20112353982..2356975 [-], 299460681499hypothetical protein 
12BF20122356980..2357648 [-], 66960681500hypothetical protein  PAAR
13BF20132357670..2359520 [-], 185160681501hypothetical protein  VgrG
14BF20142359546..2361363 [-], 181860681502hypothetical protein  TssF
15BF20152361394..2361834 [-], 44160681503bacteriophage Gp25 protein  TssE
16BF20162361831..2362289 [-], 45960681504hypothetical protein 
17BF20172362294..2362713 [-], 42060681505hypothetical protein  Hcp
18BF20182362716..2363123 [-], 40860681506hypothetical protein  Hcp
19BF20192363137..2364114 [-], 97860681507hypothetical protein 
20BF20202364119..2364985 [-], 86760681508hypothetical protein 
21BF20212364997..2365404 [-], 40860681509hypothetical protein  Hcp
22BF20222365431..2365859 [-], 42960681510hypothetical protein  Hcp
23BF20232365875..2368358 [-], 248460681511ATP-dependent protease  ClpV
24BF20242368371..2369750 [-], 138060681512hypothetical protein  TssC
25BF20252369766..2370215 [-], 45060681513hypothetical protein  TssB
26BF20262370304..2370693 [-], 39060681514hypothetical protein  Hcp
27BF20272371134..2371874 [-], 74160681515hypothetical protein 
28BF20282372222..2373493 [+], 127260681516aminotransferase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 






N/A
N/A
(1) Russell AB et al. (2014). A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism. Cell Host Microbe. 16(2):227-36. [PudMed:25070807] experimental in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation