I. Summary
SecReT6 ID91 insolico
StrainBurkholderia pseudomallei 1710b
Repliconchromosome I [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BURPS1710b_36233946654..3946923 [+], 27076810884hypothetical protein 
2BURPS1710b_36243947026..3947256 [+], 23176809925hypothetical protein 
3BURPS1710b_36253947329..3949140 [+], 181276810719secretion protein 
4BURPS1710b_36263949098..3951416 [+], 231976811842colicin V processing peptidase 
5BURPS1710b_36273949158..3951434 [-], 227776809872hypothetical protein 
6BURPS1710b_36283951422..3952861 [+], 144076810995TolC family type I secretion outer membrane protein 
7BURPS1710b_36293953071..3954039 [-], 96976811923hypothetical protein 
8BURPS1710b_36303954051..3955016 [+], 96676811061hypothetical protein 
9BURPS1710b_36313955167..3955280 [+], 11476810211hypothetical protein 
10BURPS1710b_36323955288..3959181 [+], 389476811402hypothetical protein  TssM
11BURPS1710b_36343959016..3960689 [-], 167476808560hypothetical protein 
12BURPS1710b_36333959178..3960167 [+], 99076810704hypothetical protein 
13BURPS1710b_36353960172..3961104 [+], 93376809643OmpA family domain-containing protein  TagL
14BURPS1710b_36363961303..3962424 [-], 112276810760hypothetical protein  TssA
15BURPS1710b_3638 (clpB)3962514..3965183 [-], 267076811406protease associated ATPase ClpB  TssH
16BURPS1710b_36393965217..3966317 [-], 110176809753hypothetical protein  TssG
17BURPS1710b_36403966281..3968119 [-], 183976811212hypothetical protein  TssF
18BURPS1710b_36413968199..3968681 [-], 48376810056hypothetical protein  TssE
19BURPS1710b_36423968739..3969242 [-], 50476811211hypothetical protein  TssD
20BURPS1710b_36433969315..3970805 [-], 149176810765hypothetical protein  TssC
21BURPS1710b_36443969444..3971018 [+], 157576810518hypothetical protein 
22BURPS1710b_3645 (evpA)3970822..3971340 [-], 51976809082EvpA protein  TssB
23BURPS1710b_36463971377..3972048 [-], 67276811300lipoprotein 
24BURPS1710b_36473972422..3973036 [+], 61576808921lipoprotein  TssJ
25BURPS1710b_36483973145..3974491 [+], 134776809706hypothetical protein  TssK
26BURPS1710b_36493974611..3975273 [+], 66376810780hypothetical protein  TssL
27BURPS1710b_36503975375..3975740 [+], 36676809990phage tail completion protein 
28BURPS1710b_36513976762..3977364 [-], 60376808626DNA methylase 
29BURPS1710b_36523977262..3977675 [-], 41476809194phage tail protein I 
30BURPS1710b_36533977668..3978012 [-], 34576809128phage baseplate assembly protein 
31BURPS1710b_36543980318..3981532 [+], 121576812054gp30 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
BTH_I2697 , BTH_I0068, BTH_I2693, BCAL0343, BTH_I2698, BTH_I2705, BTH_II0310, BTH_I3225, BTH_I3225, BTH_II0090, BTH_II0090

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS1710b_17691918773..1922108 [+], 333676809334hypothetical protein BTH_I2697
2BURPS1710b_0291298606..299214 [+], 60976809724hypothetical protein BTH_I0068
3BURPS1710b_17711924245..1927085 [+], 284176810168Rhs element Vgr protein BTH_I2693
4BURPS1710b_36423968739..3969242 [-], 50476811211hypothetical protein BCAL0343
5BURPS1710b_17681916256..1918664 [+], 240976811269hypothetical protein BTH_I2698
6BURPS1710b_17661910603..1913410 [+], 280876812027Rhs element Vgr protein BTH_I2705
7BURPS1710b_A11401422034..1422732 [+], 69976818674lectin BTH_II0310
8BURPS1710b_A0207310141..312906 [-], 276676818982Rhs element Vgr protein BTH_I3225
9BURPS1710b_A15821927567..1930143 [+], 257776819042Rhs element Vgr protein BTH_I3225
10BURPS1710b_A15841930276..1932462 [+], 218776819188hypothetical protein BTH_II0090
11BURPS1710b_A0205307887..310073 [-], 218776819556hypothetical protein BTH_II0090

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Proteins        Genes

Homology Immunity protein list

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS1710b_0292299201..299569 [+], 36976808937lipoprotein BTH_I0069

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Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation