SecReT6
I. Summary
SecReT6 ID910 experimental
StrainFlavobacterium johnsoniae UW101
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_009441
Location3892562..3923100
CommentA T6SS Pathway Exports Antibacterial Effectors; T6SS Mediates Interspecies Bacterial Antagonism;
Functionanti-bacterial; effector translocation
T6SS TypeType iii
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
ComponentVgrGClpVTssBTssCTssETssFTssGTssKTssN
Number111111111
ComponentTssOTssPHcp
Number112
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1FJOH_RS168603890555..3891481 [-], 927500935482FecR domain-containing protein 
2FJOH_RS168653891596..3892153 [-], 558500935484RNA polymerase sigma-70 factor 
3FJOH_RS168703892562..3894397 [-], 1836500935486type VI secretion system baseplate subunit TssF  TssF
4FJOH_RS168753894394..3894747 [-], 3541520340544carboxypeptidase-like regulatory domain-containing protein 
5FJOH_RS168803894891..3895379 [-], 489500935488hypothetical protein 
6FJOH_RS168853895387..3895947 [-], 561500935490hypothetical protein  Fti1 (i)
7FJOH_RS168903895944..3897596 [-], 1653500935492hypothetical protein  Fte1 (e)
8FJOH_RS168953897690..3898187 [-], 498500935494hypothetical protein 
9FJOH_RS169003898194..3899840 [-], 1647500935496DUF3289 family protein 
10FJOH_RS169053899844..3901652 [-], 1809500935498type IV secretion protein Rhs  VgrG
11FJOH_RS169103901691..3902086 [-], 396500935500hypothetical protein  Hcp
12FJOH_RS169153902237..3902623 [-], 387500935502hypothetical protein  Hcp
13FJOH_RS169203902805..3903236 [-], 432500935504GPW/gp25 family protein  TssE
14FJOH_RS169253903250..3903963 [-], 714500935506hypothetical protein 
15FJOH_RS169303904022..3904549 [-], 528500935508hypothetical protein 
16FJOH_RS169353904650..3906020 [-], 1371500935510type VI secretion system contractile sheath protein TssC  TssC
17FJOH_RS169403906041..3906490 [-], 450500935512hypothetical protein  TssB
18FJOH_RS169453906545..3907057 [-], 513500935514hypothetical protein  TssO
19FJOH_RS169503907083..3908252 [-], 1170500935516hypothetical protein  TssK
20FJOH_RS169553908526..3909506 [-], 981500935518hypothetical protein 
21FJOH_RS169603909608..3910762 [-], 1155500935520SH3 domain-containing protein 
22FJOH_RS169653910884..3911552 [-], 669500935522hypothetical protein 
23FJOH_RS169703911564..3912304 [-], 741500935524hypothetical protein 
24FJOH_RS169753912310..3915042 [-], 2733500935526hypothetical protein  Fjoh_3274 (e)
25FJOH_RS169803915054..3915548 [-], 495500935528DUF4280 domain-containing protein 
26FJOH_RS169853915601..3916674 [-], 1074500935530LysM peptidoglycan-binding domain-containing protein 
27FJOH_RS169903916691..3917662 [-], 972500935532TssN family type VI secretion system protein  TssN
28FJOH_RS169953917665..3918609 [-], 945500935534type VI secretion system baseplate subunit TssG  TssG
29FJOH_RS170003918593..3919234 [-], 642763168155C40 family peptidase 
30FJOH_RS170053919581..3920633 [+], 1053500935538PKD domain-containing protein  TssP
31FJOH_RS170103920641..3923100 [+], 2460500935540ATP-dependent Clp protease ATP-binding subunit  ClpV
32FJOH_RS170153923199..3923441 [-], 243917987358hypothetical protein 
33FJOH_RS170203923481..3925880 [-], 2400500935545arylsulfatase 
34FJOH_RS170253925903..3927384 [-], 1482500935547DUF1254 domain-containing protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
Fjoh_3257 (Fte1) , Fjoh_3260, Fjoh_3262, Fjoh_3274

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes

Homology Immunity protein list
Fjoh_3256 (Fti1)

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes
(1) Russell AB et al. (2014). A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism. Cell Host Microbe. 16(2):227-36. [PudMed:25070807] experimental in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation