I. Summary
SecReT6 ID92 insolico
StrainBurkholderia pseudomallei 1710b
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BURPS1710b_A0523710622..710798 [-], 17776817884hypothetical protein 
2BURPS1710b_A0524710900..711925 [+], 102676817355N-acetylmuramoyl-L-alanine amidase 
3BURPS1710b_A0525711922..712035 [-], 11476817398hypothetical protein 
4BURPS1710b_A0526 (tibC)712053..713453 [+], 140176819374hypothetical protein 
5BURPS1710b_A0527712227..713705 [-], 147976819735hypothetical protein 
6BURPS1710b_A0528713890..715026 [+], 113776818786Hep_Hag family protein 
7BURPS1710b_A0529715106..715483 [+], 37876818668hypothetical protein 
8BURPS1710b_A0530715726..717609 [-], 188476818412ImpA-like N-terminal family protein  TssA
9BURPS1710b_A0531 (virG)717606..718343 [-], 73876817810DNA-binding response regulator  VirG
10BURPS1710b_A0532718340..720169 [-], 183076819512sensor histidine kinase  VirA
11BURPS1710b_A0534720164..722446 [+], 228376817580hypothetical protein  TssC
12BURPS1710b_A0533720429..720923 [+], 49576818313hypothetical protein  TssB
13BURPS1710b_A0535722666..723175 [+], 51076819388hypothetical protein  TssD
14BURPS1710b_A0536723102..723653 [-], 55276817532hypothetical protein 
15BURPS1710b_A0537723168..723629 [+], 46276817808hypothetical protein  TssE
16BURPS1710b_A0538723666..725408 [+], 174376818402hypothetical protein  TssF
17BURPS1710b_A0539725396..726418 [+], 102376818774hypothetical protein  TssG
18BURPS1710b_A0540726405..729533 [+], 312976819348ATP-dependent Clp protease, ATP-binding subunit ClpB  TssH
19BURPS1710b_A0541729560..732583 [+], 302476819027Rhs element Vgr protein  TssI
20BURPS1710b_A0542732609..735251 [+], 264376819579hypothetical protein 
21BURPS1710b_A0543735269..736333 [+], 106576817838hypothetical protein 
22BURPS1710b_A0544736312..737082 [+], 77176818346hypothetical protein 
23BURPS1710b_A0545737140..739740 [+], 260176817929hypothetical protein  TssK
24BURPS1710b_A0546739737..740402 [+], 66676819179hypothetical protein  TssL
25BURPS1710b_A0549740509..744408 [+], 390076818261hypothetical protein  TssM
26BURPS1710b_A0547742130..742243 [+], 11476819403hypothetical protein 
27BURPS1710b_A0548742256..742453 [+], 19876818689hypothetical protein 
28BURPS1710b_A0550744424..746364 [+], 194176819789hypothetical protein  BMAA0729 (e)
29BURPS1710b_A0551745242..745670 [-], 42976817554hypothetical protein 
30BURPS1710b_A0552 (folE)746775..747458 [+], 68476819007GTP cyclohydrolase I 
31BURPS1710b_A0553747572..747895 [+], 32476819810putative transposase 
32BURPS1710b_A0554748519..750048 [-], 153076819070hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
BMAA0737 , BMAA0742, BMAA0729

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS1710b_A0541729560..732583 [+], 302476819027Rhs element Vgr protein BMAA0737
2BURPS1710b_A0535722666..723175 [+], 51076819388hypothetical protein BMAA0742
3BURPS1710b_A0550744424..746364 [+], 194176819789hypothetical protein BMAA0729

Download FASTA format files
Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation