I. Summary

SecReT6 ID	93
Strain	Burkholderia pseudomallei 1710b
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_007435
Location	1490546..1526760
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BURPS1710b_A1184	1485572..1486813 [-], 1242	76817752	ABC transporter substrate-binding protein
2	BURPS1710b_A1185	1486849..1488093 [-], 1245	76817968	maltose ABC transporter ATP-binding protein
3	BURPS1710b_A1186	1488447..1490195 [-], 1749	76819381	hypothetical protein
4	BURPS1710b_A1187	1490546..1491700 [-], 1155	76818590	LacI family regulatory protein
5	BURPS1710b_A1188 (tnpA)	1492009..1492266 [+], 258	76818286	Tn501 transposition transposase
6	BURPS1710b_A1189	1493037..1493783 [+], 747	76817438	hypothetical protein
7	BURPS1710b_A1190	1494243..1494839 [+], 597	76818748	invertase/recombinase protein
8	BURPS1710b_A1191 (rhsA2)	1494515..1495792 [-], 1278	76819503	hypothetical protein
9	BURPS1710b_A1192	1495734..1496444 [-], 711	76818332	hypothetical protein
10	BURPS1710b_A1193	1496460..1498655 [-], 2196	76817766	Rhs element Vgr protein	TssI
11	BURPS1710b_A1194	1498661..1501327 [-], 2667	76819843	SciG protein	TssH
12	BURPS1710b_A1195	1501306..1502784 [-], 1479	76817888	hypothetical protein	TssG
13	BURPS1710b_A1196	1502781..1504652 [-], 1872	76819652	hypothetical protein	TssF
14	BURPS1710b_A1197	1504657..1505217 [-], 561	76818158	hypothetical protein	TssE
15	BURPS1710b_A1198	1505236..1505727 [-], 492	76819304	hypothetical protein	TssD
16	BURPS1710b_A1199	1505787..1507295 [-], 1509	76818570	hypothetical protein	TssC
17	BURPS1710b_A1200	1507288..1507866 [-], 579	76818502	hypothetical protein	TssB
18	BURPS1710b_A1201	1507929..1509008 [-], 1080	76817764	ImpA-like N-terminal family protein	TssA
19	BURPS1710b_A1202	1509061..1511712 [-], 2652	76817651	serine/threonine protein kinase
20	BURPS1710b_A1203	1511923..1512828 [-], 906	76819515	hypothetical protein
21	BURPS1710b_A1204	1512834..1516463 [-], 3630	76818019	SciS protein	TssM
22	BURPS1710b_A1206	1516445..1518211 [+], 1767	76818860	hypothetical protein
23	BURPS1710b_A1205	1516466..1517782 [-], 1317	76817452	hypothetical protein	TssL
24	BURPS1710b_A1207	1517798..1519162 [-], 1365	76818810	protein ImpJ	TssK
25	BURPS1710b_A1208	1519198..1519773 [-], 576	76817500	putative lipoprotein	TssJ
26	BURPS1710b_A1209	1520224..1520757 [+], 534	76819333	putative lipoprotein
27	BURPS1710b_A1210	1520812..1522248 [+], 1437	76819320	FHA domain-containing protein	Fha
28	BURPS1710b_A1211	1522291..1524057 [-], 1767	76818562	hypothetical protein
29	BURPS1710b_A1212	1522345..1524399 [+], 2055	76818475	hypothetical protein
30	BURPS1710b_A1213	1523993..1524484 [+], 492	76817737	hypothetical protein
31	BURPS1710b_A1214	1524664..1525908 [+], 1245	76818895	hypothetical protein
32	BURPS1710b_A1215	1525981..1526535 [+], 555	76817243	chorismate lyase
33	BURPS1710b_A1217	1526471..1527247 [-], 777	76817469	protamine P1
34	BURPS1710b_A1216	1526584..1526760 [+], 177	76817976	hypothetical protein
35	BURPS1710b_A1218 (fabG)	1527292..1527996 [-], 705	76818672	short chain dehydrogenase/reductase family oxidoreductase
36	BURPS1710b_A1219	1528178..1529092 [+], 915	76819263	LysR family transcriptional regulator
37	BURPS1710b_A1220 (dsdA)	1529246..1530583 [-], 1338	76818241	D-serine dehydratase
38	BURPS1710b_A1221	1530680..1531621 [+], 942	76818083	LysR family transcriptional regulator

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

N/A

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

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