SecReT6
SecReT6 ID939
StrainVibrio alginolyticus 12G01
RepliconT6SS [Browse all T6SS(s) in this replicon]
Location
Comment
Functionanti-bacterial
.

Homology Effector list
V12G01_16147 , V12G01_01430, V12G01_01560, V12G01_16927, V12G01_03170, V12G01_18282   v12G01_02265, V12G01_18287, V12G01_01435, V12G01_16152, V12G01_01565, V12G01_16922

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

Download FASTA format files
Proteins        Genes

Homology Immunity protein list
   v12G01_02260
Homology immunity protein (immunity protein label, when available)
The information on regulator interaction.

#homolog effector locus tagRegulator wayFunctionRegulate targetDescription
1V12G01-18672 (vqsA)V12G01-14830 (aphA) promoter.
2V12G01-18672 (vqsA)V12G01-18672 (vqsA) promotor.
3V12G01-18672 (vqsA)QS+V12G01-21538 (luxR) promoterEMSAs and DNase I footprinting assay on both strands of PvqsA confirmed vqsA Bindind Site (VBS).
4V12G01_10813 (AsnC)V12G01-14830 (aphA) promoter.
5V12G01_10813 (AsnC)QSV12G01-21538 (luxR) promoterTranscriptional regulator AsnC, identified to bind to the promoters of both aphA and luxR.
6V12G01_02325 (HP)V12G01-14830 (aphA) promoter.
7V12G01_02325 (HP)QSV12G01-21538 (luxR) promoterTranscriptional activator, identified to bind to the promoters of both aphA and luxR.
8V12G01_01665 (HP)V12G01-14830 (aphA) promoter.
9V12G01_01665 (HP)QSV12G01-21538 (luxR) promoterHypothetical regulator,identified to bind to the promoters of both aphA and luxR.
10V12G01_06711 (HP)V12G01-14830 (aphA) promoter.
11V12G01_06711 (HP)QSV12G01-21538 (luxR) promoterLysR family protein, identified to bind to the promoters of both aphA and luxR.
12V12G01_16177 (MetR)V12G01-14830 (aphA) promoter.
13V12G01_16177 (MetR)QSV12G01-21538 (luxR) promoterLysR family MetR, identified to bind to the promoters of both aphA and luxR.
14V12G01_02620 (SoxR)V12G01-14830 (aphA) promoter.
15V12G01_02620 (SoxR)V12G01-18672 (vqsA) promotorEMSAs and DNase l footprinting assay on both strands of PvqsA confirmed LuxR Bindind Site (RBS).
16V12G01_02620 (SoxR)V12G01-18672 (vqsA) promotorEMSAs and DNase l footprinting assay on both strands of PvqsA confirmed aphA Bindind Site (ABS).
17V12G01_02620 (SoxR)QSV12G01-21538 (luxR) promoterSoxR protein, identified to bind to the promoters of both aphA and luxR.
18V12G01_21538 (LuxR)Transcription regulator+T6SS2 transcriptsTfoX and LuxR co-regulate the T6SS2.
19V12G01_19736 (TfoX)Transcription regulator+T6SS2 transcriptsTfoX specificly regulates T6SS2.
20V12G01_20658 (TfoY)Transcription regulator+T6SS transcriptsTfoY is a universal T6SS inducer in V.alginolyticus.
21V12G01_20201 (H-NS)Transcription regulator-VaT6SS1 transcriptsH-NS is a repressor of VaT6SS1 activity.
(1) Salomon D et al. (2015). Type VI Secretion System Toxins Horizontally Shared between Marine Bacteria. PLoS Pathog. 11(8):e1005128. [PudMed:26305100] experimental
(2) Salomon D et al. (2014). Marker for type VI secretion system effectors. Proc Natl Acad Sci U S A. 111(25):9271-6. [PudMed:24927539] experimental in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation