I. Summary

SecReT6 ID	94
Strain	Burkholderia pseudomallei 1710b
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_007435
Location	1948636..1990080
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	2	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	0	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BURPS1710b_A1595	1943828..1945681 [+], 1854	76819030	Hep_Hag family protein
2	BURPS1710b_A1596	1945748..1947235 [-], 1488	76818382	hypothetical protein
3	BURPS1710b_A1597	1947497..1948051 [-], 555	76817853	hypothetical protein
4	BURPS1710b_A1598 (fimA4)	1948636..1949181 [+], 546	76819245	frimbrial protein
5	BURPS1710b_A1599 (staB)	1949261..1949983 [+], 723	76818373	chaperone protein EcpD
6	BURPS1710b_A1600	1950099..1952840 [+], 2742	76818889	outer membrane usher protein
7	BURPS1710b_A1601	1952742..1952966 [-], 225	76817499	hypothetical protein
8	BURPS1710b_A1602	1952842..1953405 [+], 564	76818341	major fimbrial subunit protein
9	BURPS1710b_A1603	1953449..1954126 [+], 678	76817325	hypothetical protein	TssL
10	BURPS1710b_A1604 (ompA2)	1954129..1955805 [+], 1677	76819194	OmpA family protein	TagL
11	BURPS1710b_A1605	1956195..1956734 [+], 540	76819078	hypothetical protein	TssB
12	BURPS1710b_A1606	1956768..1958267 [+], 1500	76817314	hypothetical protein	TssC
13	BURPS1710b_A1607	1958467..1958949 [+], 483	76819763	hypothetical protein	TssD
14	BURPS1710b_A1608	1959532..1960974 [+], 1443	76818799	hypothetical protein	TssK
15	BURPS1710b_A1609	1960971..1962272 [+], 1302	76818070	hypothetical protein	TssL
16	BURPS1710b_A1610 (sciS)	1962287..1966195 [+], 3909	76818330	SciS protein	TssM
17	BURPS1710b_A1611	1966226..1966348 [+], 123	76817597	hypothetical protein
18	BURPS1710b_A1612	1966385..1966954 [+], 570	76818362	hypothetical protein
19	BURPS1710b_A1613	1967052..1969628 [+], 2577	76817637	Rhs element Vgr protein	TssI
20	BURPS1710b_A1614	1969703..1969972 [+], 270	76819204	Rhs family protein	PAAR
21	BURPS1710b_A1615	1969985..1973437 [+], 3453	76818340	Rhs1 protein
22	BURPS1710b_A1616	1973330..1974724 [-], 1395	76819079	hypothetical protein
23	BURPS1710b_A1617	1974527..1974619 [+], 93	76817816	hypothetical protein
24	BURPS1710b_A1618	1974721..1975749 [-], 1029	76819533	hypothetical protein
25	BURPS1710b_A1619	1975804..1976874 [-], 1071	76818907	ImpA-like N-terminal family protein	TssA
26	BURPS1710b_A1620	1976893..1977942 [-], 1050	76818593	hypothetical protein	TssG
27	BURPS1710b_A1621	1977939..1979819 [-], 1881	76818079	hypothetical protein	TssF
28	BURPS1710b_A1622	1979821..1980339 [-], 519	76818466	hypothetical protein	TssE
29	BURPS1710b_A1623 (sciE)	1980326..1981180 [-], 855	76817875	SciE protein	TagJ
30	BURPS1710b_A1624	1981164..1982219 [-], 1056	76818970	hypothetical protein
31	BURPS1710b_A1625 (sciG)	1982538..1985294 [+], 2757	76818455	SciG protein	TssH
32	BURPS1710b_A1626	1985557..1985676 [+], 120	76818717	hypothetical protein
33	BURPS1710b_A1627 (rcsC)	1985685..1988651 [-], 2967	76817983	two-component system sensor protein
34	BURPS1710b_A1628	1989401..1989661 [+], 261	76819234	hypothetical protein
35	BURPS1710b_A1629	1989988..1990080 [+], 93	76819143	hypothetical protein
36	BURPS1710b_A1630	1990332..1990994 [-], 663	76818490	DNA-binding response regulator
37	BURPS1710b_A1631	1991543..1994110 [-], 2568	76817744	putative fimbrial usher protein
38	BURPS1710b_A1632 (fimC1)	1994288..1994998 [-], 711	76818165	putative periplasmic chaperone protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

N/A

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

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