I. Summary

SecReT6 ID	95
Strain	Burkholderia pseudomallei 1710b
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_007435
Location	2053579..2087109
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	BURPS1710b_A1679 (pvcA)	2050054..2051112 [+], 1059	76818400	pyoverdine chromophore biosynthetic protein PvcA
2	BURPS1710b_A1680 (pvcB)	2051109..2052023 [+], 915	76818821	pyoverdine chromophore biosynthetic protein PvcB
3	BURPS1710b_A1681 (pvcC)	2052049..2053533 [+], 1485	76817901	pyoverdin chromophore biosynthetic protein PvcC
4	BURPS1710b_A1682 (asnB)	2053579..2055447 [+], 1869	76817861	asparagine synthase
5	BURPS1710b_A1684	2055392..2057467 [-], 2076	76817344	hypothetical protein
6	BURPS1710b_A1685	2055463..2057889 [+], 2427	76819474	hypothetical protein
7	BURPS1710b_A1683	2055476..2056447 [+], 972	76819510	quinone oxidoreductase
8	BURPS1710b_A1686	2056502..2057428 [+], 927	76819023	putative dioxygenase
9	BURPS1710b_A1687 (ptxR)	2057672..2059033 [-], 1362	76819569	LysR family transcriptional regulator
10	BURPS1710b_A1688	2059272..2059475 [+], 204	76817475	hypothetical protein
11	BURPS1710b_A1689 (sciS)	2059856..2063932 [-], 4077	76818042	SciS protein	TssM
12	BURPS1710b_A1690	2063961..2065226 [-], 1266	76819105	hypothetical protein	TssL
13	BURPS1710b_A1691	2065315..2066661 [-], 1347	76818318	hypothetical protein	TssK
14	BURPS1710b_A1692	2066683..2067186 [-], 504	76819028	putative lipoprotein	TssJ
15	BURPS1710b_A1693	2067293..2067778 [-], 486	76819777	hypothetical protein	TssD
16	BURPS1710b_A1694	2067895..2069487 [-], 1593	76817264	hypothetical protein	TssC
17	BURPS1710b_A1695	2069429..2073145 [-], 3717	76817970	hypothetical protein	TssB
18	BURPS1710b_A1696 (sciG)	2070046..2072973 [-], 2928	76818832	SciG protein	TssH
19	BURPS1710b_A1697	2073479..2074225 [+], 747	76817991	hypothetical protein
20	BURPS1710b_A1698	2074222..2075187 [+], 966	76818111	ImpE protein superfamily protein	TagJ
21	BURPS1710b_A1699	2075174..2075755 [+], 582	76817523	hypothetical protein	TssE
22	BURPS1710b_A1700	2075786..2077675 [+], 1890	76819516	SciC protein	TssF
23	BURPS1710b_A1701	2077675..2078760 [+], 1086	76819180	SciB protein	TssG
24	BURPS1710b_A1702	2078757..2079860 [+], 1104	76819067	ImpA-like N-terminal family protein	TssA
25	BURPS1710b_A1703	2079932..2082259 [+], 2328	76818495	Rhs element Vgr protein	TssI
26	BURPS1710b_A1704	2082180..2084768 [+], 2589	76819210	pentapeptide repeat-containing protein
27	BURPS1710b_A1705	2084765..2085847 [+], 1083	76818653	pentapeptide repeat-containing protein
28	BURPS1710b_A1706	2086029..2086688 [+], 660	76818273	hypothetical protein
29	BURPS1710b_A1707	2086729..2087109 [+], 381	76818805	hypothetical protein
30	BURPS1710b_A1709	2087745..2089970 [+], 2226	76818439	hypothetical protein
31	BURPS1710b_A1708	2087811..2089727 [-], 1917	76819385	hypothetical protein
32	BURPS1710b_A1710	2090067..2090960 [-], 894	76819531	LysR family transcriptional regulator
33	BURPS1710b_A1711	2090960..2091832 [+], 873	76818980	quinone reductase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

N/A

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

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