SecReT6
Effector Protein ID: 83717090
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SecReT6 ID113
T6SS typeA1
Gene symbol-
Locus tagBTH_II0863
StrainBurkholderia thailandensis E264
Repliconchromosome II [GenBank: NC_007650] [Browse all T6SS(s) in this replicon]
Location [Strand]1009425..1012463 [-]
ProductRhs element Vgr protein
Effector typeProtein
Homologous effectorBMAA0737
Descriptiontype VI secretion system Vgr family protein; Required for host cell fusion and virulence
UniProt IDQ2T6Y9
KEGG IDbte:BTH_II0863
PDB IDNA
Domain hit(s) vs Pfam Phage_GPD [PF05954], Evalue: 5.30E-65, Aligned region: 58..361
Phage_base_V [PF04717], Evalue: 1.70E-16, Aligned region: 408..501
Protein Sequence: 1012 a.a.     [Download]
>gi|83717090|ref|YP_439060.1| unnamed protein product [Burkholderia thailandensis E264]
MSSSHRHYADTALADVAALTDAASRADAAPLANARRFTFASTAYDAATFDVVDIDGRDAISQPYRFEITL
VSRSVRIDFAKMLSCEATLAILPPFGEAGTTRYAGVLAEFEQKERFRDFTVYRAALVPRLWRLSLYKASD
VYLNEQTIPDIVKRVLRAASFGKRNFRMRHRGVYRKRSFVCQYDESHLDFVSRWMEKEGLYYYFEHDGRR
EKLEIVDDRRDQPGPADDLALRYLPATCLDAGIESDRVQAFACRATPLPREVVLRDFNHRKAELSLEVRE
HVAHDGVGERVSSDEHFHTKDEGRRYAKLRAEALVCEGRRFAGESTAAGLRAGRFFALSGHYRKDFDGRY
LVTAVTHRGSQAHLLFPDLDAPFGATPGEPVYRAEFEAIAANLQYRPPRTTPKPRAAGVVSAIVDGEGSG
KRAELDEHGQYKVRFPFAHTAHPTNKASARIRMATPYAGDDRGMHLPLLKRTEVKIAFDGGDPDRPVIVG
AVPNSSHRSVVTRSNPDAHRILTEHNQLYMKDGSGAATWLHAPNNHIGIGAVGPGDGLALLTSGNKFDFS
LGNAYSFSGGLKCSVSMGGNTDIYVGVRNSLDVSANFLTTLQGNLRWMLPGSRSFEINDSASTLLQTLHK
QSATGAIRLSAGQDASALLQKQLDKLKGTVRKFMIVSGLANAGAAATAAGLIKGGGALADLPWAGFGVSA
AQFAGATGFSTALMATSRTLLSKIAKLQEALPLVADLSLDKQGIALAAKNLTHATRMSLTVDGVSWSTHA
KGPGAAGAAMSVGKGRWGVEAAEHAHVHANDTLLFAVPADPTSKFDLKELIGLRRDLDECVKGIADLEAD
ISENEVLSTDQNTFGVGALVPTPPSPANAVAAVAIKAKEAKLVELNAKRKLVATKIDNLQQKLAKHAKNL
SAARMSASDAEVGFKGNRLVATAEGVTLAHAQGKAKLDVREAKIGVEAGKSSLELDESKLAAGCGGASLK
LGSDGAIDVRATNVKLNGSASLKLDGQLIQLG
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Nucleotide Sequence: 3039 bp     [Download]
>gi|83716035|ref|NC_007650.1|:c1012463-1009425 Burkholderia thailandensis E264 chromosome II, complete sequence
ATGTCTTCGTCCCATCGACACTACGCCGACACGGCGCTCGCGGATGTCGCGGCGCTCACGGATGCCGCGT
CGCGCGCCGACGCCGCGCCGCTCGCGAACGCGCGACGCTTCACGTTCGCGAGCACCGCGTACGACGCTGC
CACGTTCGACGTCGTCGACATCGACGGCCGCGACGCGATCTCGCAGCCGTACCGGTTCGAGATCACGCTC
GTGAGCAGGAGTGTGCGGATCGACTTCGCGAAGATGCTGAGTTGCGAGGCGACGCTCGCGATCCTGCCGC
CGTTCGGTGAGGCCGGCACGACCCGCTATGCCGGCGTGCTCGCCGAATTCGAGCAGAAGGAACGCTTTCG
CGACTTCACCGTCTATCGCGCGGCGCTCGTGCCGCGCCTCTGGCGCCTCTCGCTGTACAAGGCGTCGGAC
GTCTACCTGAACGAGCAGACGATTCCCGATATCGTCAAGCGCGTGCTGCGCGCCGCGTCGTTCGGCAAGC
GCAATTTCCGCATGCGGCACCGCGGCGTCTACCGCAAGCGCAGCTTCGTCTGCCAGTACGACGAGAGCCA
TCTCGATTTCGTGTCGCGCTGGATGGAGAAGGAAGGCCTCTACTACTACTTCGAGCATGACGGCCGACGC
GAAAAGCTCGAGATCGTTGACGACCGCCGCGACCAGCCCGGCCCCGCCGACGATCTCGCGCTGCGCTACC
TACCCGCCACCTGTCTCGACGCGGGCATCGAATCGGACCGCGTGCAGGCGTTCGCATGCCGCGCGACGCC
GCTGCCGCGCGAGGTCGTGCTGCGCGATTTCAACCACCGCAAGGCGGAGCTGTCGCTCGAAGTCCGCGAG
CACGTGGCGCACGACGGCGTCGGCGAGCGGGTATCGAGCGACGAGCATTTCCACACGAAGGACGAAGGGC
GGCGCTACGCGAAGCTGCGCGCCGAGGCGCTCGTTTGCGAAGGCCGCCGTTTCGCCGGCGAATCGACCGC
GGCCGGGCTGCGCGCGGGCCGCTTCTTCGCGCTCTCGGGCCACTACCGCAAGGACTTCGACGGCCGCTAT
CTGGTGACGGCGGTCACGCATCGCGGCTCGCAGGCGCACCTGCTGTTTCCCGATCTCGACGCGCCGTTCG
GCGCGACGCCGGGCGAGCCCGTCTACCGCGCCGAGTTCGAGGCGATCGCCGCCAACCTCCAGTACCGGCC
GCCGCGCACGACGCCGAAGCCGCGCGCGGCGGGCGTCGTCAGCGCGATCGTCGACGGCGAGGGCAGCGGC
AAGCGCGCCGAACTCGACGAACACGGCCAGTACAAAGTGCGCTTTCCGTTCGCGCACACCGCGCATCCGA
CGAACAAGGCCTCCGCGCGCATCCGGATGGCGACGCCCTATGCGGGCGACGACCGCGGCATGCATCTGCC
GCTTCTGAAGCGCACCGAAGTGAAGATCGCATTCGACGGCGGCGATCCGGACCGCCCCGTGATCGTCGGC
GCGGTGCCCAACTCGTCGCACCGCAGCGTCGTCACGCGCAGCAACCCCGACGCGCACCGGATCCTCACCG
AGCACAACCAGCTCTACATGAAGGACGGCAGCGGCGCGGCGACGTGGCTGCACGCGCCGAACAACCACAT
CGGCATCGGCGCGGTCGGGCCGGGCGACGGCCTCGCGCTCCTCACGTCCGGCAACAAGTTCGATTTCTCG
CTCGGCAACGCGTACAGCTTCTCGGGCGGGCTCAAGTGCTCGGTGTCGATGGGCGGCAACACCGACATCT
ACGTCGGCGTGCGCAACAGCCTCGACGTCAGCGCGAACTTCCTGACGACGCTGCAGGGCAACCTGCGCTG
GATGCTGCCCGGCAGCCGAAGCTTCGAGATCAACGACAGCGCGTCCACGCTGCTGCAGACGCTGCACAAG
CAGTCCGCGACGGGCGCGATCCGGCTGTCCGCCGGGCAGGACGCGTCCGCGCTGCTGCAAAAGCAGCTCG
ACAAGCTCAAGGGCACGGTGCGCAAGTTCATGATCGTGTCGGGCCTCGCGAACGCCGGAGCCGCGGCCAC
CGCTGCGGGGCTCATCAAGGGCGGCGGCGCGCTCGCCGATCTGCCGTGGGCGGGCTTCGGCGTGTCCGCC
GCGCAGTTCGCCGGCGCGACCGGCTTCAGCACGGCGCTGATGGCGACCTCGCGCACGCTGCTCTCGAAAA
TCGCGAAGCTCCAGGAGGCGTTGCCGCTCGTCGCCGATCTATCGCTCGACAAGCAAGGCATCGCGCTCGC
GGCGAAGAACCTCACGCACGCGACGCGGATGTCGCTCACCGTCGACGGCGTCTCGTGGTCGACGCACGCG
AAGGGGCCGGGCGCGGCAGGCGCCGCGATGAGCGTCGGCAAGGGCCGCTGGGGCGTCGAAGCGGCGGAGC
ACGCGCATGTCCACGCGAATGACACGCTGCTGTTCGCCGTGCCGGCCGACCCAACGAGCAAGTTCGACCT
CAAGGAGCTGATCGGGCTGCGCCGCGATCTCGACGAATGCGTGAAGGGTATCGCCGATCTCGAAGCCGAC
ATTTCGGAAAACGAAGTGCTTTCGACCGATCAGAACACGTTCGGCGTCGGCGCGCTCGTGCCCACGCCGC
CGTCGCCCGCCAATGCGGTCGCGGCGGTCGCGATCAAGGCGAAGGAAGCGAAGCTCGTCGAGCTGAACGC
CAAACGCAAGCTCGTCGCGACGAAGATCGACAACCTCCAGCAGAAGCTCGCGAAGCACGCGAAGAACCTG
AGCGCCGCGCGGATGAGCGCGTCGGACGCGGAAGTCGGCTTCAAGGGCAACCGGCTCGTCGCGACGGCCG
AAGGCGTCACGCTCGCGCATGCGCAGGGCAAGGCGAAGCTCGACGTGCGCGAGGCGAAGATCGGCGTCGA
GGCAGGCAAATCGAGCCTCGAGCTCGACGAGAGCAAGCTCGCGGCCGGCTGCGGCGGCGCCTCGCTGAAG
CTGGGCAGCGACGGCGCGATCGACGTGCGCGCGACTAACGTCAAGCTGAACGGCAGCGCGTCGCTGAAGC
TCGACGGACAGTTGATCCAGCTAGGCTGA

Reference
(1) Schwarz S et al. (2014). VgrG-5 is a Burkholderia type VI secretion exported protein required for multinucleated giant cell formation and virulence. Infect Immun. 82(4):1445-52. [PudMed:24452686] experimental
 
experimental experimental literature