Thiopeptide:GE2270 (Series d)  ChemDraw eXchange file 
Genotype:Type III (No MIA (indolyl), no QA (quinolinic acid))
Antibiotics: Antimicrobial;
Gram Nature: Gram+,Gram-;
Target Organism: Staphylococcus aureus (MIC=0.06µg/ml );
Staphylococcus aureus methicillin resistant (MIC=0.03µg/ml);
Coagulase-negative staphylococci, methicillin resistant (MIC=0.125µg/ml);
Staphylococcus saprophyticus (MIC=0.125µg/ml);
Streptococcus agalactiae (MIC=1µg/ml);
Streptococcus pneumoniae (MIC=0.25µg/ml);
Enterococcus faecalis (MIC=0.03µg/ml);
Enterococcus faecium, vancomycin resistant (MIC=0.03µg/ml);
Anticancer:[Patent: WO2002066046]
Producer Organism:Planobispora rosea ATCC 53773;
Reference: Selva, et al. (1991). Antibiotic GE2270 a: a novel inhibitor of bacterial protein synthesis. I. Isolation and characterization. J Antibiot (Tokyo). 44(7):693-701. [PudMed:1908853]  
link More details
(1) GE2270A     GE2270A JEPG file GE2270A ChemDraw eXchange file   gene cluster experimental PubChem Link 
CAS: 134861-34-0
 Producer Organism:  Nonomuraea sp. WU8817;
(2) GE2270B1     GE2270B1 JEPG file GE2270B1 ChemDraw eXchange file  
CAS: 139351-31-8P
(3) GE2270B2     GE2270B2 JEPG file GE2270B2 ChemDraw eXchange file  
CAS: 139351-32-9P
(4) GE2270C1     GE2270C1 JEPG file GE2270C1 ChemDraw eXchange file  
CAS: 139351-33-0P
(5) GE2270C2a     GE2270C2a JEPG file GE2270C2a ChemDraw eXchange file  
CAS: 145118-96-3P
(6) GE2270C2b     GE2270C2b JEPG file GE2270C2b ChemDraw eXchange file  
CAS: 139351-34-1P
(7) GE2270D1     GE2270D1 JEPG file GE2270D1 ChemDraw eXchange file  
CAS: 138948-59-1P
(8) GE2270D2     GE2270D2 JEPG file GE2270D2 ChemDraw eXchange file  
CAS: 138948-60-4P
(9) GE2270E     GE2270E JEPG file GE2270E ChemDraw eXchange file  
CAS: 138948-61-5P
(10) GE2270T     GE2270T JEPG file GE2270T ChemDraw eXchange file  
CAS: 138967-24-5P

structure: Structure in JEPG file
ChemDraw eXchange file: ChemDraw eXchange file
PubChem Link: PubChem Link
gene cluster: Biosynthetic gene cluster identified
experimental: Data derived from experimental literature