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Gene Symbol:  
CDPW8_1946
Organism:  
Corynebacterium diphtheriae PW8
Gene Cluster:  
    gene cluster
Position [Strand], Length:  
2063272..2065872 [1], 2601 bp
Product Function:  
lantibiotic dehydratase domain-containing protein
Product Locus:  
 YP_005143497.1  [GenBank Link]
Homologue:   
(of the nosiheptide biosynthetic proteins)  
NosE in Streptomyces actuosus ATCC 25421
  
Nucleotide Sequence:2601 bp
>CDPW8_1946|ThioFinder1485 Corynebacterium diphtheriae PW8
ATGACAACTACTTCATGGAAACTTCTTAATGAGGCCTTGGTTCGCAGCTGCAGTGTGCCGTATGAGGCGT
TACGCCAGCTTTGCGACGCCCCCACCGACGCACTACTTACTGCCGATCTGGACCAGCGACTCCGCGTAAA
CGCGGCCCTTGATGCCCTTGGTTCTGCGGCCCATCAGGACGTCGCGGGGTGCACAAACACAGTGTTGCGT
CGGGCTCTACTCGATCTCAAACGAGCTGCACATCATCATGACGTGCGCAAAGTTCGTGCCCTGCTGGCTA
AAGCTACATCCGCTGGTGTGCGGTTGCCTGCTGGCGTAACGGCTGCCGCAGATACGGTGATCACTGCCGC
CGAAAACGTGCTGTCCTCAGAGCAGCTGCACAAGGTACTCATGAGTTCCAAGAAAAGAGAGCGCGAGTGC
CTCGGGAAGATTGCCCGTGACTGGGGAGTCGATTCAGCAGTACTGGCTGCATCAGTCCCAGCGGCAAAAG
CCATCCGGAAACTGAGCACAGATTGTGCGCTGTCTGCCAAGCAGCTAGCTCGTGCCCACCGCACCGCGCT
GGGATACGTGATCCGCAGCGCCACCCGGTCAGTACCGTTTTCCGCCCTGTGCGCAATCGCGCCGTCTCAG
TTGTCCCACGCCAGCCTACACTCGGATGAGACTCTTGCCCCAACATCTGTGCACACTATTGCGCGTTGGA
ACGTCTACGCCATGGCTCAGATTTTCTCTGCTATGAAGAAGGACTTTGGTTTTATTGCCACACTTCCGGT
TCTGGCTAATCCTGACGCGTTATCAGAGCATGGTCACTGCGTACTGCCTCGGTGTTCTGTCGAATATCTA
GGGCACGTCGGCGACCGGGACTTGGCCGTTTACCGGGAGGAACGCCGAGTGGTCGATTCCAATGGACTAT
TTGGAAAGGTCATGGCCTTAGCCACAAGTGCTCCCCAAAACCACGAATATACGTGTGAGCAGCTGGCCGC
AGAGCTCTCGGCGCGTACAGGTTTAAGCAAGGCACAAACAAAGTGCATTGTTCTCGATGCCATCCGAATT
TCGGCCTTAGTTGTTCCCACTCTCGATTTATCCCCGTCCACAGCGGTATCTGAACAGCCGATAGTTACGC
ACTTGGCACGTGGGTCGGACAAGGCCGTATCTGCTGCGCGTCTCATTGCCCGCATCACGGAGGAATGCAA
CGCGGTGGCGTCGATAAGCGACTTTGACCGCAGGCGCACTCAGATCCTAGATCTCGCGCACCACCTAGAT
AGCCTCCGGCGACTCGTCGATCCCAGCATGCCGGTGTTCCATACCCATGTGTATGAGGATGGGGTCGGGA
AAGAATCGACGATTCCCTCCTCCATCGTGGACTCGTGCACAGACCTTGACTGGGAAGCTCTCGCAGACCT
AGTCGATCTGCTTGATGTGCGGCAGGCAGAACGCGCGTTGTTTGAGGAGTTTGTGTCCGCAAAATTCCCC
CGTGGGGAAATCTGCCACGATGTTCCGGCGGTGGTCAATAGTTTTGTCTCCGAGGTCCTCACGCCGCTGC
GGCAGGTTGATATTGAGGCAGTTGATGAAAATGACCTGAAGTCCACTGCATCGTTGCCACTGGGTAAGGC
ATGGGAATGGATTCGGGCGCGGCGCCGCTTCCTGGCACACGTAACCGAGTTAAGAAACAACGCCGCTGGT
CCCGTGGATATACGGAATCTCCTCACCAACTATCGTCCACTTGTGCAGTCTCGTAGGTATCCGCTTCGAT
CTTTAAACGTATACGTTCAGCAAGGCGACGAGGCCAAAGTCGTGATTAACCGGACGCTCGGCGGCCCAGG
CTTCCCGTGGTCTCGGTTCGCGCATGCGATGCCGGATTCCGCAGCACGCGCATGGTCCGAATTATCGGAT
TATGCGTCTGACGCTGGGGTGACGCTTGTCGAGTTGACAGCCGGAAAAGTGGTCTCCAACCTCAACGCAC
ATCCGGCCACCTACCCAACCACTCTCCTCATCCCAGGACATCCTCGAAAAACCACACGGTCGTCTGATAT
TCGACTCGCAGACACGCAGTTGGCCTACTGCGCATCCAGCGGACGCTTGCAGCTTTTCGACGCCCACGGC
ACCGAACTCCTCCCCGCATACATGGGATACATCACTGACCGGGGACTGCCATTATCTACGCAAGTCCTCA
TGCTCTTAGCGCCACCCATGCATTGTTCCTTGGACTTTTTCCCGCGCACGAGTTCAGAGATAATGCATCA
GGCTCGTCTACTCCTAGGAGATGTTGTTCTTGCGCGAGAAAGCTGGATTTTTCCCACCTCAAGCACCTCT
ATGGATATTCCGTGTCTCCTAGAAGAGGCACTGGTGTGGTGGCGCAGCATTGCCCGACATCACGACCTAC
CCGAGTGCGGAGTTCTGCGAACATTCGATGCCCACGGCGTTGTGGGTAAAGGACAGTTTTATAACTCCCA
AATCATGGGAACGATCACCAACCTCATACGCGCATTGCGCAACGCTCACTACGGGTTTGTGATTGAGGAA
TTCTTTCCCCACGCCAGCGCGTCCGGTGTAGCACAGGAATACATAGTCACAGGAACGCGCTCTCTGAAGG
AGGGTATCTAA
 Primer design

Protein Sequence:866 a.a.
>CDPW8_1946|ThioFinder1485 Corynebacterium diphtheriae PW8
MTTTSWKLLNEALVRSCSVPYEALRQLCDAPTDALLTADLDQRLRVNAALDALGSAAHQDVAGCTNTVLR
RALLDLKRAAHHHDVRKVRALLAKATSAGVRLPAGVTAAADTVITAAENVLSSEQLHKVLMSSKKREREC
LGKIARDWGVDSAVLAASVPAAKAIRKLSTDCALSAKQLARAHRTALGYVIRSATRSVPFSALCAIAPSQ
LSHASLHSDETLAPTSVHTIARWNVYAMAQIFSAMKKDFGFIATLPVLANPDALSEHGHCVLPRCSVEYL
GHVGDRDLAVYREERRVVDSNGLFGKVMALATSAPQNHEYTCEQLAAELSARTGLSKAQTKCIVLDAIRI
SALVVPTLDLSPSTAVSEQPIVTHLARGSDKAVSAARLIARITEECNAVASISDFDRRRTQILDLAHHLD
SLRRLVDPSMPVFHTHVYEDGVGKESTIPSSIVDSCTDLDWEALADLVDLLDVRQAERALFEEFVSAKFP
RGEICHDVPAVVNSFVSEVLTPLRQVDIEAVDENDLKSTASLPLGKAWEWIRARRRFLAHVTELRNNAAG
PVDIRNLLTNYRPLVQSRRYPLRSLNVYVQQGDEAKVVINRTLGGPGFPWSRFAHAMPDSAARAWSELSD
YASDAGVTLVELTAGKVVSNLNAHPATYPTTLLIPGHPRKTTRSSDIRLADTQLAYCASSGRLQLFDAHG
TELLPAYMGYITDRGLPLSTQVLMLLAPPMHCSLDFFPRTSSEIMHQARLLLGDVVLARESWIFPTSSTS
MDIPCLLEEALVWWRSIARHHDLPECGVLRTFDAHGVVGKGQFYNSQIMGTITNLIRALRNAHYGFVIEE
FFPHASASGVAQEYIVTGTRSLKEGI