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Homologues of NosF
#OrganismProteinFunction
 1Streptomyces actuosus ATCC 25421NosFNADH oxidase
 2Nocardia sp. ATCC 202099NocFdehydrogenase
 3Streptomyces laurentii ATCC 31255TsrMNADH oxidase
 4Streptomyces sioyaensis ATCC 13989SioMNADH oxidase
 5Nocardiopsis sp. TFS65-07TpaEputative thiazoline/oxazoline dehydrogenase
 6Streptomyces hygroscopicus 10-22CltCmcbC-like oxidoreductase
 7Nonomuraea sp. Bp3714-39TpdEdehydrogenase
 8Nonomuraea sp. WU8817TpdEdehydrogenase
 9Bacillus cereus ATCC 14579BC5081NADH oxidase
 10Propionibacterium acnes KPA171202PPA0864hypothetical protein
 11Catenulispora acidiphila DSM 44928Caci_4206nitroreductase
 12Catenulispora acidiphila DSM 44928Caci_3691hypothetical protein
 13Salinispora tropica CNB-440Strop_2434hypothetical protein
 14Salinispora arenicola CNS-205Sare_2589hypothetical protein
 15Streptomyces griseus subsp. griseus NBRC 13350SGR_4411hypothetical protein
 16Thermobispora bispora DSM 43833Tbis_0553hypothetical protein
 17Sorangium cellulosum 'So ce 56'Sce9069hypothetical protein
 18Actinosynnema mirum DSM 43827Amir_3865hypothetical protein
 19Verrucosispora maris AB-18-032VAB18032_21130nitroreductase
 20Frankia sp. CcI3Francci3_4199hypothetical protein
 21Corynebacterium pseudotuberculosis FRC41Cpfrc_01625hypothetical protein
 22Lysinibacillus sphaericus C3-41Bsph_4010hypothetical protein
 23Herpetosiphon aurantiacus ATCC 23779Haur_0920hypothetical protein
 24Clostridium cellulovorans 743BClocel_3628SagB-type dehydrogenase domain
 25Streptomyces venezuelae ATCC 10712SVEN_5137hypothetical protein
 26Streptomyces bingchenggensis BCW-1SBI_02227hypothetical protein
 27Propionibacterium acnes HL030PA1HMPREF9601_02029conserved hypothetical protein
 28Micromonospora sp. ATCC 39149MCAG_03943nitroreductase
 29Streptomyces sp. CSSNG_06378conserved hypothetical protein
 30Streptomyces griseus XylebKG-1SACT1_4710nitroreductase
 31Actinomyces viscosus C505HMPREF0059_01142hypothetical protein
 32Streptomyces sp. AA4SSMG_08018conserved hypothetical protein
 33Streptomyces pristinaespiralis ATCC 25486SSDG_06097predicted protein
 34Bacillus cereus G9241BCE_G9241_0526conserved hypothetical protein protein
 35Bacillus sp. B14905BB14905_21673hypothetical protein
 36Bacillus cereus NVH0597-99BC059799_0528hypothetical protein
 37Lactobacillus gasseri JV-V03HMPREF0514_11734conserved hypothetical protein
 38Propionibacterium acnes SK187HMPREF1034_2452bacteriocin biosynthesis cyclodehydratase domain protein
 39Actinomyces sp. oral taxon 170 str. F0386HMPREF9056_02778conserved domain protein
 40Corynebacterium pseudotuberculosis I19CpI19_1627(cltC)McbC-like_oxidoreductase
 41Streptococcus pneumoniae INV104INV104_02890unnamed protein product; Raw score 2.93
 42Streptomyces albus J1074SSHG_03897conserved hypothetical protein
 43Bacillus cereus BDRD-Cer4 Bcere0015_51780similar to NADH oxidase (NOXASE) of Bacillus cereus ATCC 14579 UniRef RepID=Q815Q4_BACCR
 44Actinomadura melliaura SCC 1655ORF5NADH oxidase
 45Streptomyces sp. NRRL 30471Mur4dehydrogenase
 46Streptomyces laurentii ATCC 31255TsrFMcbC-like protein
 47Bacillus atrophaeus 1942BATR1942_14115hypothetical protein
 48Corynebacterium ulcerans 809CULC809_01697hypothetical protein
 49Corynebacterium ulcerans BR-AD22CULC22_01775hypothetical protein
 50Streptococcus downei F0415HMPREF9176_0866SagB-type dehydrogenase domain protein
 51Lysinibacillus fusiformis ZC1BFZC1_19185putative cytoplasmic protein
 52Propionibacterium sp. 434-HC2HMPREF9948_1494bacteriocin biosynthesis cyclodehydratase domain protein
 53Streptomyces sp. ATCC 55365GetGdehydrogenase
 54Corynebacterium pseudotuberculosis 3/99-5Cp3995_1662Nitroreductase
 55Corynebacterium diphtheriae INCA 402CDB402_1841Nitroreductase
 56Corynebacterium diphtheriae CDCE 8392CDCE8392_1864Nitroreductase
 57Corynebacterium diphtheriae HC03CDHC03_1855Nitroreductase
 58Corynebacterium diphtheriae PW8CDPW8_1945Nitroreductase
 59Corynebacterium diphtheriae 31ACD31A_1973Nitroreductase
 60Corynebacterium diphtheriae BH8CDBH8_1948Nitroreductase
 61Corynebacterium diphtheriae C7CDC7B_1944Nitroreductase
 62Corynebacterium pseudotuberculosis 316Cp316_1661Nitroreductase
 63Corynebacterium pseudotuberculosis P54B96CpP54B96_1648Nitroreductase
 64Streptomyces chartreusis NRRL 12338SchaN1_010100008075hypothetical protein
Protein:   NosF, dehydrogenase
Conserved Domains
 PF00881, Nitroreductase, Nitroreductase family
Homology analysis using profile hidden Markov models
    Construct profile HMM(s): eleven sequences of NosF homologues experimentally reported, NosF.fasta
    link HMMER3 profile HMM file: NosF.hmm
    Generate HMM-logos with link LogoMat-M
NumberSequenceMultiple Alignment by link MUSCLE
 64Fasta  DNA   Protein
(1)Yu Y et al (2009). Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework. ACS Chem Biol. 4(10):855-64. [PudMed:19678698]
(2)Ding Y et al (2010). Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099. Mol Biosyst. 6(7):1180-5. [PudMed:20473441]
(3)Liao R et al (2009). Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications.. Chem Biol. 16(2):141-7. [PudMed:19246004]
(4)Morris RP et al (2009). Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.. J Am Chem Soc.. 131(16):5946-55. [PudMed:19338336]
(5)Morris RP et al (2009). Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.. J Am Chem Soc.. 131(16):5946-55. [PudMed:19338336]
(6)Engelhardt K et al (2010). Isolation and characterization of the gene cluster for biosynthesis of the thiopeptide antibiotic TP-1161.. Appl Environ Microbiol.. 76(21):7093-101.. [PudMed:20851988]
(7)Liao R et al (2009). Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications.. Chem Biol. 16(2):141-7. [PudMed:19246004]
(8)Kelly WL et al (2009). Thiostrepton biosynthesis: prototype for a new family of bacteriocins. J Am Chem Soc. 131(12):4327-34. [PudMed:19265401]
(9)Wang J et al (2010). Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22. Appl Environ Microbiol. 76(7):2335-44. [PudMed:20154110]
(10)Wieland Brown LC et al (2009). Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. Proc Natl Acad Sci U S A. 106(8):2549-53. [PudMed:19196969]
(11)Young TS et al (2011). Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans. Proc Natl Acad Sci U S A. . [PudMed:21788474]